Cideb Deficiency Aggravates Dextran Sulfate Sodium-induced Ulcerative Colitis in Mice by Exacerbating the Oxidative Burden in Colonic Mucosa.

Related Articles Cideb Deficiency Aggravates Dextran Sulfate Sodium-induced Ulcerative Colitis in Mice by Exacerbating the Oxidative Burden in Colonic Mucosa. Inflamm Bowel Dis. 2017 Aug;23(8):1338-1347 Authors: Sun C, Zhao Y, Gao X, Yuan Y, Wang C, Wang Y, Zhang L, Gu Y, Zhang F, Hu P, Wang Z, Li Z, Shi J, Li S, Cao K, Ren B, Yu M, Liang W, Li Z, Ye J Abstract BACKGROUND: Abnormal lipid metabolism is one of many factors that contribute to the development of ulcerative colitis (UC). As a lipid droplet-associated protein,…

Read More

The Association Between Maternal Chronic Inflammatory Bowel Disease and Long-term Health Outcomes in Children-A Nationwide Cohort Study.

Related Articles The Association Between Maternal Chronic Inflammatory Bowel Disease and Long-term Health Outcomes in Children-A Nationwide Cohort Study. Inflamm Bowel Dis. 2017 Aug;23(8):1440-1446 Authors: Jølving LR, Nielsen J, Beck-Nielsen SS, Nielsen RG, Friedman S, Kesmodel US, Nørgård BM Abstract BACKGROUND: Very little is known about the long-term impact of maternal inflammatory bowel disease (IBD) on the offspring’s future health. We aimed to examine whether children born to mothers with IBD had an increased risk of long-term morbidities. METHODS: In this nationwide register-based cohort study, including all children born alive…

Read More

Risk of Postoperative Complications Among Inflammatory Bowel Disease Patients Treated Preoperatively With Vedolizumab.

Related Articles Risk of Postoperative Complications Among Inflammatory Bowel Disease Patients Treated Preoperatively With Vedolizumab. Am J Gastroenterol. 2017 Jul 18;: Authors: Yamada A, Komaki Y, Patel N, Komaki F, Aelvoet AS, Tran AL, Pekow J, Dalal S, Cohen RD, Cannon L, Umanskiy K, Smith R, Hurst R, Hyman N, Rubin DT, Sakuraba A Abstract OBJECTIVES: Vedolizumab is increasingly used to treat patients with ulcerative colitis (UC) and Crohn’s disease (CD), however, its safety during the perioperative period remains unclear. We compared the 30-day postoperative complications among patients treated preoperatively…

Read More

Role of new endoscopic techniques in inflammatory bowel disease management: Has the change come?

Role of new endoscopic techniques in inflammatory bowel disease management: Has the change come? World J Gastroenterol. 2017 Jun 28;23(24):4324-4329 Authors: Goran L, Negreanu L, Negreanu AM Abstract Despite significant therapeutic progress in recent years, inflammatory bowel disease (IBD), which includes Crohn’s disease and ulcerative colitis, remains a challenge regarding its pathogenesis and long-term complications. New concepts have emerged in the management of this disease, such as the “treat-to-target” concept, in which mucosal healing plays a key role in the evolution of IBD, the risk of recurrence and the need…

Read More

Intestinal anti-inflammatory activity of Ground Cherry (Physalis angulata L.) standardized CO2 phytopharmaceutical preparation.

Intestinal anti-inflammatory activity of Ground Cherry (Physalis angulata L.) standardized CO2 phytopharmaceutical preparation. World J Gastroenterol. 2017 Jun 28;23(24):4369-4380 Authors: Almeida Junior LD, Quaglio AEV, de Almeida Costa CAR, Di Stasi LC Abstract AIM: To investigate the effects of Ground Cherry (Physalis angulata L.) standardized supercritical CO2 extract in trinitrobenzenesulphonic acid (TNBS) model of rat intestinal inflammation. METHODS: The animals were divided into groups that received vehicle or P. angulata extract (PACO2) orally at the doses 25, 50 and 100 mg/kg daily by 5 d before TNBS damage. Protective effects…

Read More

Oral and upper gastrointestinal Crohn’s disease.

Oral and upper gastrointestinal Crohn’s disease. J Gastroenterol Hepatol. 2017 Jul 14;: Authors: Laube R, Liu K, Schifter M, Yang JL, Suen MK, Leong RW Abstract Crohn’s disease is a heterogeneous, inflammatory condition that can affect any location of the gastrointestinal tract. Proximal gastrointestinal involvement occurs in 0.5-16% of patients, and it is usually diagnosed after recognition of intestinal disease. Symptoms are often mild and non-specific, however upper gastrointestinal disease predicts a more severe Crohn’s phenotype with a greater frequency of complications such as obstruction and perforation. Gastroscopy and biopsy…

Read More
<< Go Back