Rosacea may be tied to increased risk for inflammatory bowel disease

There was an increased risk for inflammatory bowel disease in patients with rosacea, according to study results published in the Journal of the American Academy of Dermatology.Researchers in Taiwan used the Taiwanese National Health Insurance Research Database to identify 89,356 patients with rosacea and 178,712 matched patients without rosacea (reference cohort) between 1997 and 2013 for analysis. The two cohorts were compared for cumulative incidences of inflammatory bowel disease (IBD). FULL ARTICLE: http://zpr.io/PAcQX

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Childhood IBD risk not affected by maternal infections, antibiotic use during pregnancy

Children born to mothers who acquired an infection requiring antibiotics during pregnancy do not have an increased risk for developing inflammatory bowel disease, according to the results of a Canadian population-based study.This finding led investigators to suggest that other events affecting the gut microbiome later in childhood may have a more important impact on a child’s risk for IBD. FULL ARTICLE: http://zpr.io/PAcFw

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FMT for UC induces remission at low dose, short duration

Fecal microbiota therapy that was prepared anaerobically from pooled donor material was more effective than placebo at 1 week for inducing remission in patients with active ulcerative colitis, according to data from an Australian randomized controlled trial presented at the 12th Congress of the European Crohn’s and Colitis Organization.To investigate whether FMT with a lower treatment burden is effective in UC, investigators randomly assigned 73 patients with active UC to receive either anaerobically prepared donor stool pooled from three or four donors (n = 38) or autologous FMT as placebo…

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Hyperbaric oxygen therapy benefits hospitalized UC patients

Hyperbaric oxygen therapy was effective, safe and well tolerated in hospitalized patients with ulcerative colitis experiencing moderate-to-severe disease flares, according to data from a randomized, double blind, sham-controlled trial presented at the 12th Congress of the European Crohn’s and Colitis Organization.As dysregulated tissue hypoxia response plays a key role in the pathogenesis of ulcerative colitis, and because hospitalized UC patients often require a second-line therapy, such as colectomy or biologics, for non-response to steroids, Corey Siegel, MD, MS, director of the Dartmouth-Hitchcock Inflammatory Bowel Disease Center in New Hampshire, Parambir…

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