Humira effective in Crohn’s patients with symptomatic small bowel strictures

About two-thirds of patients with Crohn’s disease and symptomatic small bowel stricture had a successful response to treatment with Humira, and long-term success was maintained in almost half of responders, according to results from the CREOLE study.“In this study, attempting to address a significant clinical problem in an area of unmet need, we showed that [Humira (adalimumab, AbbVie)] treatment was successful in 64% of [Crohn’s disease] patients with symptomatic stricture at week 24,” investigators wrote. “Success was maintained in 29% of the whole cohort after a median follow-up time of nearly 4 years.”