Crohn’s Disease associated Strictures.

Crohn’s Disease associated Strictures.

J Gastroenterol Hepatol. 2018 Feb 10;:

Authors: Wo WCP, Mourad F, Leong RWL

Abstract
Crohn’s disease (CD) is a chronic relapsing and remitting disease that can affect any segments of the gastrointestinal (GI) tract. More than 50% of patients with CD develop stricturing or penetrating complications within the first 10 years after diagnosis. Strictures can lead to intestinal obstruction, which is a common indication for surgery. Despite significant advances in the understanding of the pathogenesis of intestinal fibrostenosis, imaging and therapeutic armamentarium of CD, the risk of intestinal surgery remained significantly high. Endoscopic balloon dilation is a promising first-line alternative to surgery as it is less invasive and could preserve intestinal length. In this review we will evaluate the literature on the mechanism of intestinal fibrosis, emerging imaging techniques and management strategies for Crohn’s disease associated strictures.

PMID: 29427364 [PubMed – as supplied by publisher]

PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/29427364?dopt=Abstract