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Histologic scoring indices for evaluation of disease activity in ulcerative colitis.

Related Articles Histologic scoring indices for evaluation of disease activity in ulcerative colitis. Cochrane Database Syst Rev. 2017 May 25;5:CD011256 Authors: Mosli MH, Parker CE, Nelson SA, Baker KA, MacDonald JK, Zou GY, Feagan BG, Khanna R, Levesque BG, Jairath V Abstract BACKGROUND: Disease activity can be determined using clinical, endoscopic or histologic criteria in patients with ulcerative colitis (UC). Persistent disease activity is associated with poor outcomes. Histologic disease activity has been shown to be associated with relapse, colectomy and colorectal cancer. The ability to objectively evaluate microscopic disease…

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Clinical Characteristics and Long-term Prognosis of Elderly-onset Ulcerative Colitis.

Related Articles Clinical Characteristics and Long-term Prognosis of Elderly-onset Ulcerative Colitis. J Gastroenterol Hepatol. 2017 May 19;: Authors: Song EM, Lee HS, Park SH, Kim GU, Seo MS, Hwang SW, Yang DH, Kim KJ, Byeon JS, Myung SJ, Yang SK, Ye BD Abstract BACKGROUND: The aim of this study was to investigate the clinical characteristics and prognosis of patients with elderly-onset ulcerative colitis (EOUC), a new growing subgroup of UC. METHODS: We retrospectively analyzed 3,060 South Korean UC patients diagnosed between 1977 and 2014. The clinical characteristics and prognosis of…

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One-day Behavioral Intervention for Patients with Inflammatory Bowel Disease and Co-Occurring Psychological Distress.

Related Articles One-day Behavioral Intervention for Patients with Inflammatory Bowel Disease and Co-Occurring Psychological Distress. Clin Gastroenterol Hepatol. 2017 May 19;: Authors: Hou JK, Vanga RR, Thakur E, Gonzalez I, Willis D, Dindo L PMID: 28532699 [PubMed – as supplied by publisher] PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/28532699?dopt=Abstract

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Extracolonic Cancer in Inflammatory Bowel Disease: Data from the GETECCU Eneida Registry.

Extracolonic Cancer in Inflammatory Bowel Disease: Data from the GETECCU Eneida Registry. Am J Gastroenterol. 2017 May 23;: Authors: Chaparro M, Ramas M, Benítez JM, López-García A, Juan A, Guardiola J, Mínguez M, Calvet X, Márquez L, Fernández Salazar LI, Bujanda L, García C, Zabana Y, Lorente R, Barrio J, Hinojosa E, Iborra M, Cajal MD, Van Domselaar M, García-Sepulcre MF, Gomollón F, Piqueras M, Alcaín G, García-Sánchez V, Panés J, Domènech E, García-Esquinas E, Rodríguez-Artalejo F, Gisbert JP Abstract OBJECTIVES: The objective of this study was (a) To know…

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TGF-β in inflammatory bowel disease: a key regulator of immune cells, epithelium, and the intestinal microbiota.

Related Articles TGF-β in inflammatory bowel disease: a key regulator of immune cells, epithelium, and the intestinal microbiota. J Gastroenterol. 2017 May 22;: Authors: Ihara S, Hirata Y, Koike K Abstract Inflammatory bowel disease (IBD) is defined as chronic intestinal inflammation, and includes ulcerative colitis and Crohn’s disease. Multiple factors are involved in the pathogenesis of IBD, and the condition is characterized by aberrant mucosal immune reactions to intestinal microbes in genetically susceptible hosts. Transforming growth factor-β (TGF-β) is an immune-suppressive cytokine produced by many cell types and activated by…

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Efficacy and safety of stellate ganglion block in chronic ulcerative colitis.

Related Articles Efficacy and safety of stellate ganglion block in chronic ulcerative colitis. World J Gastroenterol. 2017 May 07;23(17):3193-3194 Authors: Lipov E, Candido K Abstract Sympathetic system modulation by stellate ganglion blockade may modulate immune dysfunction and significantly improve symptoms of chronic ulcerative colitis. PMID: 28533676 [PubMed – in process] PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/28533676?dopt=Abstract

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Esophagitis and its causes: Who is “guilty” when acid is found “not guilty”?

Related Articles Esophagitis and its causes: Who is “guilty” when acid is found “not guilty”? World J Gastroenterol. 2017 May 07;23(17):3011-3016 Authors: Grossi L, Ciccaglione AF, Marzio L Abstract Esophagitis is mainly a consequence of gastroesophageal reflux disease, one of the most common diseases affecting the upper digestive tract. However the esophageal mucosa can also be targeted by some infectious, systemic or chemical conditions. Eosinophilic esophagitis (EoE) is an immune-mediated inflammatory disease, characterized by eosinophilic infiltration in the mucosa. Esophageal localization of Crohn’s disease is not very common, but it…

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