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Efficacy and safety of stellate ganglion block in chronic ulcerative colitis.

Related Articles Efficacy and safety of stellate ganglion block in chronic ulcerative colitis. World J Gastroenterol. 2017 May 07;23(17):3193-3194 Authors: Lipov E, Candido K Abstract Sympathetic system modulation by stellate ganglion blockade may modulate immune dysfunction and significantly improve symptoms of chronic ulcerative colitis. PMID: 28533676 [PubMed – in process] PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/28533676?dopt=Abstract

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Esophagitis and its causes: Who is “guilty” when acid is found “not guilty”?

Related Articles Esophagitis and its causes: Who is “guilty” when acid is found “not guilty”? World J Gastroenterol. 2017 May 07;23(17):3011-3016 Authors: Grossi L, Ciccaglione AF, Marzio L Abstract Esophagitis is mainly a consequence of gastroesophageal reflux disease, one of the most common diseases affecting the upper digestive tract. However the esophageal mucosa can also be targeted by some infectious, systemic or chemical conditions. Eosinophilic esophagitis (EoE) is an immune-mediated inflammatory disease, characterized by eosinophilic infiltration in the mucosa. Esophageal localization of Crohn’s disease is not very common, but it…

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Non-invasive evaluation of intestinal disorders: The role of elastographic techniques.

Related Articles Non-invasive evaluation of intestinal disorders: The role of elastographic techniques. World J Gastroenterol. 2017 Apr 28;23(16):2832-2840 Authors: Branchi F, Caprioli F, Orlando S, Conte D, Fraquelli M Abstract Over the recent years the non-invasive techniques for the evaluation of the small bowel have been playing a major role in the management of chronic intestinal diseases, such as inflammatory bowel diseases (IBD). The diagnostic performances of magnetic resonance imaging, computed tomography and ultrasound in the field of small bowel disorders, have been assessed and established for more than two…

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High throughput RNA sequencing utility for diagnosis and prognosis in colon diseases.

Related Articles High throughput RNA sequencing utility for diagnosis and prognosis in colon diseases. World J Gastroenterol. 2017 Apr 28;23(16):2819-2825 Authors: Gao M, Zhong A, Patel N, Alur C, Vyas D Abstract RNA sequencing is the use of high throughput next generation sequencing technology to survey, characterize, and quantify the transcriptome of a genome. RNA sequencing has been used to analyze the pathogenesis of several malignancies such melanoma, lung cancer, and colorectal cancer. RNA sequencing can identify differential expression of genes (DEG’s), mutated genes, fusion genes, and gene isoforms in…

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Protein-losing pseudomembranous colitis with cap polyposis-like features.

Related Articles Protein-losing pseudomembranous colitis with cap polyposis-like features. World J Gastroenterol. 2017 Apr 28;23(16):3003-3010 Authors: Kreisel W, Ruf G, Salm R, Lazaro A, Bengsch B, Globig AM, Fisch P, Lassmann S, Schmitt-Graeff A Abstract Protein-losing enteropathy (PLE) is characterized by loss of serum proteins into the gastrointestinal tract. It may lead to hypoproteinemia and clinically present as protein deficiency edema, ascites, pleural or pericardial effusion and/or malnutrition. In most cases the site of protein loss is the small intestine. Here we present an unusual case of severe PLE in…

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Combination of corticosteroids and 5-aminosalicylates or corticosteroids alone for patients with moderate-severe active ulcerative colitis: A global survey of physicians’ practice.

Related Articles Combination of corticosteroids and 5-aminosalicylates or corticosteroids alone for patients with moderate-severe active ulcerative colitis: A global survey of physicians’ practice. World J Gastroenterol. 2017 Apr 28;23(16):2995-3002 Authors: Ben-Horin S, Andrews JM, Katsanos KH, Rieder F, Steinwurz F, Karmiris K, Cheon JH, Moran GW, Cesarini M, Stone CD, Schwartz D, Protic M, Roblin X, Roda G, Chen MH, Har-Noy O, Bernstein CN Abstract AIM: To examine treatment decisions of gastroenterologists regarding the choice of prescribing 5-aminosalycilates (5ASA) with corticosteroids (CS) versus corticosteroids alone for patients with active ulcerative…

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Overexpression of fibrinogen-like protein 2 protects against T cell-induced colitis.

Related Articles Overexpression of fibrinogen-like protein 2 protects against T cell-induced colitis. World J Gastroenterol. 2017 Apr 21;23(15):2673-2684 Authors: Bartczak A, Zhang J, Adeyi O, Amir A, Grant D, Gorczynski R, Selzner N, Chruscinski A, Levy GA Abstract AIM: To determine the effect of overexpression of fibrinogen-like protein 2 (FGL2) on regulatory T cell (Treg) and effector T (Teff) cell function on T cell-induced colitis in Rag1(-/-) mice. METHODS: Treg and Teff cells from fgl2(-/-), fgl2(+/+), and fgl2(Tg) mice were purified by FACS. They were studied in vitro for immunosuppressive…

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Pathogenesis and clinical spectrum of primary sclerosing cholangitis.

Related Articles Pathogenesis and clinical spectrum of primary sclerosing cholangitis. World J Gastroenterol. 2017 Apr 14;23(14):2459-2469 Authors: Gidwaney NG, Pawa S, Das KM Abstract Primary sclerosing cholangitis (PSC) is a disease of the biliary tract, which has been documented in the literature since 1867. This disease has a strong predilection for affecting men and can be seen in individuals as young as 2 years of age. PSC has a strong associated with inflammatory bowel disease, more commonly with ulcerative colitis, and is also part of the clinical spectrum of IgG4-related…

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Impact of vitamin D on the hospitalization rate of Crohn’s disease patients seen at a tertiary care center.

Related Articles Impact of vitamin D on the hospitalization rate of Crohn’s disease patients seen at a tertiary care center. World J Gastroenterol. 2017 Apr 14;23(14):2539-2544 Authors: Venkata KVR, Arora SS, Xie FL, Malik TA Abstract AIM: To study the association between vitamin D level and hospitalization rate in Crohn’s disease (CD) patients. METHODS: We designed a retrospective cohort study using adult patients (> 19 years) with CD followed for at least one year at our inflammatory bowel disease center. Vitamin D levels were divided into: low mean vitamin D…

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Potential role of nutraceutical compounds in inflammatory bowel disease.

Related Articles Potential role of nutraceutical compounds in inflammatory bowel disease. World J Gastroenterol. 2017 Apr 14;23(14):2483-2492 Authors: Larussa T, Imeneo M, Luzza F Abstract Conventional therapies for inflammatory bowel diseases (IBD) involve combinations of pharmacologic agents such as aminosalicylates, azathioprine, and corticosteroids. Recently, the therapeutic scenario has been heavily increased by the introduction of agents including monoclonal antibodies targeted to specific proinflammatory cytokines, to adhesion molecules, and the induction of anti-inflammatory cytokines and T-cell activation. However, the use of these drugs is accompanied by a certain number of side…

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