Predictors of mucosal healing during induction therapy in patients with acute moderate-to-severe ulcerative colitis.

Related Articles Predictors of mucosal healing during induction therapy in patients with acute moderate-to-severe ulcerative colitis. J Gastroenterol Hepatol. 2018 Dec 14;: Authors: Motobayashi M, Matsuoka K, Takenaka K, Fujii T, Nagahori M, Ohtsuka K, Iwamoto F, Tsuchiya K, Negi M, Eishi Y, Watanabe M Abstract BACKGROUND AND AIM: The treat-to-target strategy has emerged in ulcerative colitis management. Mucosal healing is the best target, albeit not in induction therapy of acute diseases as clinical conditions vary over a short duration. To determine the targets during induction therapy for acute ulcerative…

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Disease course of inflammatory bowel disease unclassified in a European population-based inception cohort – an Epi-IBD study.

Related Articles Disease course of inflammatory bowel disease unclassified in a European population-based inception cohort – an Epi-IBD study. J Gastroenterol Hepatol. 2018 Dec 18;: Authors: Burisch J, Chetcuti Zammit S, Ellul P, Turcan S, Duricova D, Bortlik M, Winther Andersen K, Andersen V, Kaimakliotis IP, Fumery M, Gower-Rousseau C, Girardin G, Valpiani D, Goldis A, Brinar M, Čuković-Čavka S, Oksanen P, Collin P, Barros L, Magro F, Misra R, Arebi N, Eriksson C, Halfvarson J, Kievit HAL, Pedersen N, Kjeldsen J, Myers S, Sebastian S, Katsanos KH, Christodoulou DK,…

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Emerging trends of inflammatory bowel disease in South Korea: a nationwide population-based study.

Related Articles Emerging trends of inflammatory bowel disease in South Korea: a nationwide population-based study. J Gastroenterol Hepatol. 2018 Nov 16;: Authors: Kwak MS, Cha JM, Lee HH, Choi YS, Seo SI, Ko KJ, Park DI, Kim SH, Kim TJ Abstract Background and Aims Little is known regarding the exact burden of inflammatory bowel disease (IBD) in Asian countries because previous epidemiologic studies were hospital-based. We aimed to develop and validate an operational definition of IBD cases from health insurance claims data and to examine the epidemiological features of IBD…

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Ginsenoside Rb1 promotes intestinal epithelial wound healing through ERK and Rho signaling.

Ginsenoside Rb1 promotes intestinal epithelial wound healing through ERK and Rho signaling. J Gastroenterol Hepatol. 2018 Nov 05;: Authors: Toyokawa Y, Takagi T, Uchiyama K, Mizushima K, Inoue K, Ushiroda C, Kashiwagi S, Nakano T, Hotta Y, Tanaka M, Dohi O, Okayama T, Yoshida N, Katada K, Kamada K, Ishikawa T, Handa O, Konishi H, Naito Y, Itoh Y Abstract BACKGROUND AND AIM: Daikenchuto, a traditional Japanese herbal medicine, has been reported to exhibit anti-inflammatory effects against intestinal inflammation. However, whether daikenchuto has a therapeutic effect against intestinal mucosal injuries…

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Risk of Skin Cancers in Thiopurines-treated and Untreated patients with Inflammatory Bowel Disease: A Systematic Review and Meta-analysis.

Related Articles Risk of Skin Cancers in Thiopurines-treated and Untreated patients with Inflammatory Bowel Disease: A Systematic Review and Meta-analysis. J Gastroenterol Hepatol. 2018 Nov 04;: Authors: Huang SZ, Liu ZC, Liao WX, Wei JX, Huang XW, Yang C, Xia YH, Li L, Ye C, Dai SX Abstract BACKGROUND AND AIM: The thiopurines are effective in the management of patients with inflammatory bowel disease (IBD), but the association between thiopurines use and the risk of skin cancer (including nonmelanoma skin cancer [NMSC] and melanoma skin cancer [MSC]) has already been…

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Tauroursodeoxycholic acid attenuates colitis-associated colon cancer by inhibiting nuclear factor kappaB signaling.

Tauroursodeoxycholic acid attenuates colitis-associated colon cancer by inhibiting nuclear factor kappaB signaling. J Gastroenterol Hepatol. 2018 Oct 30;: Authors: Kim YH, Kim JH, Kim BG, Lee KL, Kim JW, Koh SJ Abstract BACKGROUND AND AIM: Inflammatory bowel diseases (IBD) is associated with an increased risk for the development of colorectal cancer. However, the mechanism of immune signaling pathways linked to colitis-associated cancer (CAC) has not been fully elucidated. Tauroursodeoxycholic acid (TUDCA) exhibits anti-inflammatory and anti-cancer activities. The aim of this study is to investigate the role of TUDCA in the…

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Validation of the Inflammatory Bowel Disease Disability Index for Self-report and Development of an Item-reduced Version.

Related Articles Validation of the Inflammatory Bowel Disease Disability Index for Self-report and Development of an Item-reduced Version. J Gastroenterol Hepatol. 2018 Oct 01;: Authors: Paulides E, Kim C, Frampton C, Gearry RB, Eglinton T, Leong RW, de Boer NKH, Mulder CJJ, McCombie AM Abstract BACKGROUND AND AIM: The Inflammatory Bowel Disease Disability Index (IBD-DI) is a measure of disability in IBD. The IBD-DI is validated for use as a clinical interview, but not for use as a self-report questionnaire. We aimed to validate the IBD-DI for self-report (IBD-DI-SR) and…

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Comparison of a novel predictor of venous thromboembolic complications in inflammatory bowel disease with current predictors.

Related Articles Comparison of a novel predictor of venous thromboembolic complications in inflammatory bowel disease with current predictors. J Gastroenterol Hepatol. 2018 Sep 17;: Authors: Ohta Y, Arai M, Nakagawa T, Akizue N, Ishikawa K, Hamanaka S, Koseki H, Taida T, Okimoto K, Saito K, Yoshihama S, Maruoka D, Matsumura T, Katsuno T, Kato N Abstract BACKGROUND AND AIM: Venous thromboembolism (VTE) is a common complication of inflammatory bowel disease (IBD). The aim of the present study was to identify predictors of VTE in hospitalised patients with IBD. METHODS: Patients…

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