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Clinical Characteristics and Long-term Prognosis of Elderly-onset Ulcerative Colitis.

Related Articles Clinical Characteristics and Long-term Prognosis of Elderly-onset Ulcerative Colitis. J Gastroenterol Hepatol. 2017 May 19;: Authors: Song EM, Lee HS, Park SH, Kim GU, Seo MS, Hwang SW, Yang DH, Kim KJ, Byeon JS, Myung SJ, Yang SK, Ye BD Abstract BACKGROUND: The aim of this study was to investigate the clinical characteristics and prognosis of patients with elderly-onset ulcerative colitis (EOUC), a new growing subgroup of UC. METHODS: We retrospectively analyzed 3,060 South Korean UC patients diagnosed between 1977 and 2014. The clinical characteristics and prognosis of…

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Effect of oral tobacco use and smoking on outcomes of Crohn’s disease in India.

Effect of oral tobacco use and smoking on outcomes of Crohn’s disease in India. J Gastroenterol Hepatol. 2017 May 05;: Authors: Arora U, Ananthakrishnan AN, Kedia S, Bopana S, Mouli PV, Yadav DP, Makharia GK, Yajnik V, Ahuja V Abstract INTRODUCTION: Smoking has been linked with adverse outcomes in Crohn’s disease(CD), however it is not known whether oral tobacco use affects disease outcomes in these patients. The study aimed to assess the association between smoking or oral tobacco(OT) and outcomes in CD. METHODS: Retrospective analysis was performed on prospectively maintained…

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Direct Health Care Cost Utilization in Hong Kong Inflammatory Bowel Disease Patients in the Initial 2 Years Following Diagnosis.

Direct Health Care Cost Utilization in Hong Kong Inflammatory Bowel Disease Patients in the Initial 2 Years Following Diagnosis. J Gastroenterol Hepatol. 2017 May 05;: Authors: Mak LY, Ng SC, Wong IOL, Li MKK, Lo FH, Wong MTL, Leung CM, Tsang SWC, Chan KH, Sze SF, Shan EHS, Lam BCY, Hui AJ, Hung IFN, Leung WK Abstract BACKGROUND AND AIM: There is scanty data on the healthcare utilization from Asia where the incidence of inflammatory bowel disease (IBD) is rising rapidly. We aim to determine the direct healthcare costs in…

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Endoscopic features and genetic background of inflammatory bowel disease complicated with Takayasu arteritis.

Endoscopic features and genetic background of inflammatory bowel disease complicated with Takayasu arteritis. J Gastroenterol Hepatol. 2017 May;32(5):1011-1017 Authors: Akiyama S, Fujii T, Matsuoka K, Yusuke E, Negi M, Takenaka K, Nagahori M, Ohtsuka K, Isobe M, Watanabe M Abstract BACKGROUND AND AIM: Takayasu arteritis (TA) is occasionally complicated with inflammatory bowel disease (IBD). This study assessed the endoscopic and genetic features of IBD complicated with TA (IBD-TA). METHODS: This study retrospectively reviewed the clinical charts of 142 TA patients (14 men and 128 women; median age 48.5 years [range, 18-97 years])….

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Microvesicles Shuttled miR-200b attenuate Experimental Colitis associated Intestinal Fibrosis by Inhibiting the Development of EMT.

Microvesicles Shuttled miR-200b attenuate Experimental Colitis associated Intestinal Fibrosis by Inhibiting the Development of EMT. J Gastroenterol Hepatol. 2017 Mar 31;: Authors: Yang J, Zhou CZ, Zhu R, Fan H, Liu XX, Duan XY, Tang Q, Shou ZX, Zuo DM Abstract BACKGROUND: Epithelial-mesenchymal transition (EMT), characterized by the decrease of E-Cad and increase of vimentin and α-SMA, was demonstrated to participate in inflammatory bowel disease (IBD) related fibrosis. MiR-200b plays an anti-fibrosis role in inhibiting EMT by targeting ZEB1 and ZEB2. But the stability of exogenous miR-200b in blood limits…

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Association between disease activity and quality of life in ulcerative colitis: Results from the CRONICA-UC study.

Association between disease activity and quality of life in ulcerative colitis: Results from the CRONICA-UC study. J Gastroenterol Hepatol. 2017 Mar 29;: Authors: Panés J, Domènech E, Aguas Peris M, Nos P, Riestra S, Juliá B, Cea-Calvo L, Romero C, Marín-Jiménez I Abstract BACKGROUND AND AIM: In ulcerative colitis (UC), main goals of treatment are to control disease activity and normalize health-related quality of life (HRQoL). In this study, we explored the relationship between disease activity (measured using the Simple Clinical Colitis Activity Index [SCCAI]) and patient HRQoL (measured using…

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Influence of Age at Diagnosis on the Clinical Characteristics of Crohn’s Disease in Korea: Results from the CONNECT study.

Related Articles Influence of Age at Diagnosis on the Clinical Characteristics of Crohn’s Disease in Korea: Results from the CONNECT study. J Gastroenterol Hepatol. 2017 Mar 02;: Authors: Hwang SW, Kim JH, Im JP, Ye BD, Koo HS, Huh KC, Cheon JH, Kim YS, Kim YH, Han DS, Kim WH, Kim JS, Crohn’s disease clinical network and cohort (CONNECT) study Abstract BACKGROUND AND AIM: The present study evaluated the clinical characteristics of Korean patients with Crohn’s disease (CD) according to their age at diagnosis in a nationwide multicenter cohort study….

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Gluten-induced cognitive impairment (“brain fog”) in coeliac disease.

Gluten-induced cognitive impairment (“brain fog”) in coeliac disease. J Gastroenterol Hepatol. 2017 Mar;32 Suppl 1:90-93 Authors: Yelland GW Abstract Much is known about the serious neurological effects of gluten ingestion in coeliac disease patients, such as sporadic ataxia and peripheral neuropathy, although the causal links to gluten are still under debate. However, such disorders are observed in only a small percentage of coeliac patients. Much less is known about the transient cognitive impairments to memory, attention, executive function, and the speed of cognitive processing reported by the majority of patients…

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Use of the low-FODMAP diet in inflammatory bowel disease.

Use of the low-FODMAP diet in inflammatory bowel disease. J Gastroenterol Hepatol. 2017 Mar;32 Suppl 1:40-42 Authors: Gibson PR Abstract Irritable bowel syndrome (IBS)-like symptoms are not uncommon in patients with quiescent inflammatory bowel disease (IBD). While gluten-free diet is applied by patients, there are no reported interventional studies. The low-FODMAP diet, on the other hand, has efficacy similar to that seen in patients with IBS in three unblinded or observational studies of IBD cohorts who had well-controlled inflammatory disease and in one small randomized cross-over study. FODMAP intake by…

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Using eHealth strategies in delivering dietary and other therapies in patients with irritable bowel syndrome and inflammatory bowel disease.

Using eHealth strategies in delivering dietary and other therapies in patients with irritable bowel syndrome and inflammatory bowel disease. J Gastroenterol Hepatol. 2017 Mar;32 Suppl 1:27-31 Authors: Ankersen DV, Carlsen K, Marker D, Munkholm P, Burisch J Abstract Health-care systems around the world are facing increasing costs. Non-adherent, chronically ill patients are one such expense incurred by health-care providers. Web-based home-monitoring of patients-or eHealth-has been shown to increase adherence to medical therapy, facilitate contact between patients and health-care professionals, and reduce time to remission for patients with inflammatory bowel disease…

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