Oral and upper gastrointestinal Crohn’s disease.

Oral and upper gastrointestinal Crohn’s disease. J Gastroenterol Hepatol. 2017 Jul 14;: Authors: Laube R, Liu K, Schifter M, Yang JL, Suen MK, Leong RW Abstract Crohn’s disease is a heterogeneous, inflammatory condition that can affect any location of the gastrointestinal tract. Proximal gastrointestinal involvement occurs in 0.5-16% of patients, and it is usually diagnosed after recognition of intestinal disease. Symptoms are often mild and non-specific, however upper gastrointestinal disease predicts a more severe Crohn’s phenotype with a greater frequency of complications such as obstruction and perforation. Gastroscopy and biopsy…

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Update on intestinal microbiota in Crohn’s disease 2017: Mechanisms, Clinical application, Adverse reactions and Outlook.

Update on intestinal microbiota in Crohn’s disease 2017: Mechanisms, Clinical application, Adverse reactions and Outlook. J Gastroenterol Hepatol. 2017 Jul 05;: Authors: Shen Z, Zhu C, Quan Y, Yuan W, Wu S, Yang Z, Luo W, Tan B, Wang X Abstract The pathogenesis of CD is complex and it is thought to be associated with the environment, immune, hereditary, microbe and other factors. If the balance between the host and the intestinal microbes in CD patients was broken, immune-inflammatory response of susceptible individuals might be triggered. Probiotics could improve the…

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Rediscover the clinical value of small intestinal bacterial overgrowth in patients with intestinal Behçet’s disease.

Rediscover the clinical value of small intestinal bacterial overgrowth in patients with intestinal Behçet’s disease. J Gastroenterol Hepatol. 2017 Jun 30;: Authors: Jo JH, Park SJ, Cheon JH, Kim TI, Kim WH Abstract Background/Aims Many patients with intestinal Behçet’s disease (BD) still suffer from gastrointestinal symptoms despite the disease being in endoscopic or radiological remission. Previous studies report that small intestinal bacterial overgrowth (SIBO) can be associated with inflammatory bowel disease. However, there have been no reports about SIBO in patients with intestinal BD. We sought to identify the frequency…

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Examining maintenance care following infliximab salvage therapy for acute severe ulcerative colitis.

Examining maintenance care following infliximab salvage therapy for acute severe ulcerative colitis. J Gastroenterol Hepatol. 2017 Jun 15;: Authors: Seah D, Choy MC, Gorelik A, Connell WR, Sparrow MP, van Langenberg D, Hebbard G, Moore G, De Cruz P Abstract BACKGROUND AND AIMS: Data supporting the optimal maintenance drug therapy & strategy to monitor ongoing response following successful infliximab (IFX) induction, for acute severe ulcerative colitis (ASUC), are limited. We aimed to evaluate maintenance & monitoring strategies employed in patients post IFX induction therapy. METHODS: Patients in 6 Australian tertiary…

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Gastrointestinal: Crohn’s disease in the terminal ileum with an ileo-ileal fistula: Radiologic-pathologic correlation.

Gastrointestinal: Crohn’s disease in the terminal ileum with an ileo-ileal fistula: Radiologic-pathologic correlation. J Gastroenterol Hepatol. 2017 Jun;32(6):1133 Authors: Courcoutsakis N, Karayiannakis A, Chrysafis I, Bolanaki H, Prassopoulos P PMID: 28557201 [PubMed – in process] PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/28557201?dopt=Abstract

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Assessment of factors associated with smoking cessation at diagnosis or during follow-up of Crohn’s disease.

Assessment of factors associated with smoking cessation at diagnosis or during follow-up of Crohn’s disease. J Gastroenterol Hepatol. 2017 May 26;: Authors: Song EM, Kim GU, Seo M, Hwang SW, Park SH, Kwon E, Lee HS, Yang DH, Kim KJ, Ye BD, Byeon JS, Myung SJ, Yang SK Abstract BACKGROUND AND AIMS: Smoking cessation is known to improve the course of Crohn’s disease (CD). However, the factors associated with smoking cessation after CD diagnosis have not been well established. METHODS: Clinical characteristics and change in smoking status were evaluated in…

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Clinical Characteristics and Long-term Prognosis of Elderly-onset Ulcerative Colitis.

Related Articles Clinical Characteristics and Long-term Prognosis of Elderly-onset Ulcerative Colitis. J Gastroenterol Hepatol. 2017 May 19;: Authors: Song EM, Lee HS, Park SH, Kim GU, Seo MS, Hwang SW, Yang DH, Kim KJ, Byeon JS, Myung SJ, Yang SK, Ye BD Abstract BACKGROUND: The aim of this study was to investigate the clinical characteristics and prognosis of patients with elderly-onset ulcerative colitis (EOUC), a new growing subgroup of UC. METHODS: We retrospectively analyzed 3,060 South Korean UC patients diagnosed between 1977 and 2014. The clinical characteristics and prognosis of…

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Effect of oral tobacco use and smoking on outcomes of Crohn’s disease in India.

Effect of oral tobacco use and smoking on outcomes of Crohn’s disease in India. J Gastroenterol Hepatol. 2017 May 05;: Authors: Arora U, Ananthakrishnan AN, Kedia S, Bopana S, Mouli PV, Yadav DP, Makharia GK, Yajnik V, Ahuja V Abstract INTRODUCTION: Smoking has been linked with adverse outcomes in Crohn’s disease(CD), however it is not known whether oral tobacco use affects disease outcomes in these patients. The study aimed to assess the association between smoking or oral tobacco(OT) and outcomes in CD. METHODS: Retrospective analysis was performed on prospectively maintained…

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Direct Health Care Cost Utilization in Hong Kong Inflammatory Bowel Disease Patients in the Initial 2 Years Following Diagnosis.

Direct Health Care Cost Utilization in Hong Kong Inflammatory Bowel Disease Patients in the Initial 2 Years Following Diagnosis. J Gastroenterol Hepatol. 2017 May 05;: Authors: Mak LY, Ng SC, Wong IOL, Li MKK, Lo FH, Wong MTL, Leung CM, Tsang SWC, Chan KH, Sze SF, Shan EHS, Lam BCY, Hui AJ, Hung IFN, Leung WK Abstract BACKGROUND AND AIM: There is scanty data on the healthcare utilization from Asia where the incidence of inflammatory bowel disease (IBD) is rising rapidly. We aim to determine the direct healthcare costs in…

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