Oral and Otorhinolaryngological Findings in Adults Who Were Diagnosed With Pediatric Onset Crohn’s Disease: A Controlled Study.

Oral and Otorhinolaryngological Findings in Adults Who Were Diagnosed With Pediatric Onset Crohn’s Disease: A Controlled Study. J Clin Gastroenterol. 2018 Jun 16;: Authors: Haaramo A, Alapulli H, Aine L, Tuokkola J, Saarnisto U, Roine RP, Pitkäranta A, Kolho KL Abstract BACKGROUND: Up to 50% of pediatric patients with Crohn’s disease (CD) report oral manifestations, but less is known about their oral health when they become adults. GOALS: Our aim was to provide detailed descriptions of the presence of oral and otorhinolaryngological manifestations in patients with pediatric onset CD once…

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Link Between Celiac Disease and Inflammatory Bowel Disease.

Related Articles Link Between Celiac Disease and Inflammatory Bowel Disease. J Clin Gastroenterol. 2018 May 14;: Authors: Shah A, Walker M, Burger D, Martin N, von Wulffen M, Koloski N, Jones M, Talley NJ, J Holtmann G Abstract GOAL: The aim of this analysis was to assess in patients with inflammatory bowel disease (IBD) the risk of celiac disease and in celiac disease patients the risk of IBD. BACKGROUND: Previous studies report a possible association between IBD and celiac disease; however, this link is controversial. STUDY: Using the search terms…

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Inflammatory Cytokine Profile in Crohn’s Disease Nonresponders to Optimal Antitumor Necrosis Factor Therapy.

Inflammatory Cytokine Profile in Crohn’s Disease Nonresponders to Optimal Antitumor Necrosis Factor Therapy. J Clin Gastroenterol. 2018 Mar 06;: Authors: Yarur AJ, Jain A, Quintero MA, Czul F, Deshpande AR, Kerman DH, Abreu MT Abstract BACKGROUND: A significant number of patients receiving therapy with antitumor necrosis factor (TNF) agents for Crohn’s disease experience primary or secondary nonresponse. The aim of this study was to assess whether patients with nonresponse to anti-TNF agents have increased expression of alternative cytokine pathways. METHODS: We designed a prospective, cross-sectional study that included patients with…

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Comparative Efficacy of Anti-TNF Therapies For The Prevention of Postoperative Recurrence of Crohn’s Disease: A Systematic Review and Network Meta-Analysis of Prospective Trials.

Comparative Efficacy of Anti-TNF Therapies For The Prevention of Postoperative Recurrence of Crohn’s Disease: A Systematic Review and Network Meta-Analysis of Prospective Trials. J Clin Gastroenterol. 2018 Mar 06;: Authors: Bakouny Z, Yared F, El Rassy E, Jabbour R, Hallit R, Khoury N, Honein K, Bou Jaoude J Abstract INTRODUCTION: There is a lack of studies on the optimal anti-tumor necrosis factor (anti-TNF) agent for postoperative prophylaxis of Crohn’s disease (CD) recurrence. Therefore, we conducted a network meta-analysis (NMA) of prospective trials to compare the efficacy of anti-TNF agents in…

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Crohn’s Disease: A Critical Approach to Publication Procedures and Citation Behavior of the Global Research Network.

Crohn’s Disease: A Critical Approach to Publication Procedures and Citation Behavior of the Global Research Network. J Clin Gastroenterol. 2018 Mar;52(3):246-254 Authors: Schöffel N, Brüggmann D, Klingelhöfer D, Bendels MHK, Groneberg DA Abstract BACKGROUND AND GOALS: Crohn’s disease (CD) is an inflammatory bowel disease, which can lead to abdominal pain, weight loss, fatigue, severe diarrhea, and malnutrition. Despite enormous efforts and progress in diagnosis and therapy, there are still many aspects of uncertainty leading to an increasing scientific interest in this topic. As it is challenging to survey all articles…

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Virtual Chromoendoscopy With FICE for the Classification of Polypoid and Nonpolypoid Raised Lesions in Ulcerative Colitis.

Virtual Chromoendoscopy With FICE for the Classification of Polypoid and Nonpolypoid Raised Lesions in Ulcerative Colitis. J Clin Gastroenterol. 2018 Feb 01;: Authors: Cassinotti A, Buffoli F, Fociani P, Staiano T, Villanacci V, Nebuloni M, Duca P, Fichera M, Grassia R, Manes G, Salemme M, Molteni P, Sampietro G, Foschi D, de Franchis R, Ardizzone S Abstract GOALS: The aim of this study was to analyze the performance of Fuji Intelligent Color Enhancement (FICE) using the classification of Kudo in the differentiation of neoplastic and non-neoplastic raised lesions in ulcerative…

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Fecal Matrix Metalloproteinase-9 Measurement for Optimizing Detection of Disease Activity in Inflammatory Bowel Disease.

Fecal Matrix Metalloproteinase-9 Measurement for Optimizing Detection of Disease Activity in Inflammatory Bowel Disease. J Clin Gastroenterol. 2017 Dec 18;: Authors: Kreijne JE, van der Giessen J, Verhaar AP, Peppelenbosch MM, de Vries AC, van der Woude JC, Fuhler GM PMID: 29256991 [PubMed – as supplied by publisher] PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/29256991?dopt=Abstract

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Distinct Microbial Populations Exist in the Mucosa-associated Microbiota of Diarrhea Predominant Irritable Bowel Syndrome and Ulcerative Colitis.

Distinct Microbial Populations Exist in the Mucosa-associated Microbiota of Diarrhea Predominant Irritable Bowel Syndrome and Ulcerative Colitis. J Clin Gastroenterol. 2017 Nov 28;: Authors: Zhong W, Lu X, Shi H, Zhao G, Song Y, Wang Y, Zhang J, Jin Y, Wang S Abstract GOALS: The goal of this study was to observe the bacterial colonization in the intestinal mucosa in the patients with diarrhea predominant irritable bowel syndrome (IBS-D) and ulcerative colitis (UC), and compare the mucosa-associated microbiota among the IBS-D patients, UC patients and the healthy control, and explore…

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The Impact of Clostridium difficile Infection on Mortality in Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis.

The Impact of Clostridium difficile Infection on Mortality in Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis. J Clin Gastroenterol. 2017 Dec 04;: Authors: Tariq R, Law CCY, Khanna S, Murthy S, McCurdy JD Abstract BACKGROUND AND AIMS: Clostridium difficile infection (CDI) has been associated with an increased mortality risk among patients with inflammatory bowel disease (IBD) in multiple observational studies. We performed a systematic review and meta-analysis to help clearly define the magnitude of risk in IBD patients with and without CDI, and to assess the risk…

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