Population Health Management for Inflammatory Bowel Disease.

Population Health Management for Inflammatory Bowel Disease. Gastroenterology. 2017 Nov 06;: Authors: Dulai PS, Singh S, Ohno-Machado L, Sandborn WJ Abstract Inflammatory bowel diseases (IBD) are chronic and impose significant, multi-dimensional burdens on patients and healthcare systems. The increasing prevalence of IBD will only worsen this problem globally-population health management (PHM) strategies are needed to increase quality of care and population health outcomes while reducing healthcare costs. We discuss the key components of PHM in IBD. Effective implementation of PHM strategies requires accurate identification of at-risk patients and of key…

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Incidence and Treatment of Patients Diagnosed With Inflammatory Bowel Diseases at 60 Years or Older in Sweden.

Incidence and Treatment of Patients Diagnosed With Inflammatory Bowel Diseases at 60 Years or Older in Sweden. Gastroenterology. 2017 Nov 01;: Authors: Everhov ÅH, Halfvarson J, Myrelid P, Sachs MC, Nordenvall C, Söderling J, Ekbom A, Neovius M, Ludvigsson JF, Askling J, Olén O Abstract BACKGROUND & AIMS: Diagnosis of inflammatory bowel diseases (IBD) is increasing among elderly persons (60 years or older). We performed a nationwide population-based study to estimate incidence and treatment. METHODS: We identified all incident IBD cases in Sweden, from 2006 through 2013, using national registers,…

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DNA Methylation and Transcription Patterns in Intestinal Epithelial Cells From Pediatric Patients With Inflammatory Bowel Diseases Differentiate Disease Subtypes and Associate With Outcome.

Related Articles DNA Methylation and Transcription Patterns in Intestinal Epithelial Cells From Pediatric Patients With Inflammatory Bowel Diseases Differentiate Disease Subtypes and Associate With Outcome. Gastroenterology. 2017 Oct 11;: Authors: Howell KJ, Kraiczy J, Nayak KM, Gasparetto M, Ross A, Lee C, Mak TN, Koo BK, Kumar N, Lawley T, Sinha A, Rosenstiel P, Heuschkel R, Stegle O, Zilbauer M Abstract BACKGROUND & AIMS: We analyzed DNA methylation patterns and transcriptomes of primary intestinal epithelial cells (IEC) of children newly diagnosed with inflammatory bowel diseases (IBD) to learn more about…

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A Bidirectional Relationship Between Symptom Reporting and Perceived Stress, But Not Disease Activity, in Inflammatory Bowel Disease: More Questions Than Answers?

A Bidirectional Relationship Between Symptom Reporting and Perceived Stress, But Not Disease Activity, in Inflammatory Bowel Disease: More Questions Than Answers? Gastroenterology. 2017 Oct 05;: Authors: Gracie DJ, Ford AC PMID: 28988924 [PubMed – as supplied by publisher] PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/28988924?dopt=Abstract

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Screening for Epstein-Barr Virus Status and Risk of Hemophagocytic Lymphohistiocytosis in Children With Inflammatory Bowel Disease on Azathioprine.

Screening for Epstein-Barr Virus Status and Risk of Hemophagocytic Lymphohistiocytosis in Children With Inflammatory Bowel Disease on Azathioprine. Gastroenterology. 2017 Sep 04;: Authors: Chapman S, El-Matary W PMID: 28881189 [PubMed – as supplied by publisher] PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/28881189?dopt=Abstract

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3D cross-sectional imaging of the inflamed gut with Light Sheet Fluorescence Microscopy for translational research in IBD.

Related Articles 3D cross-sectional imaging of the inflamed gut with Light Sheet Fluorescence Microscopy for translational research in IBD. Gastroenterology. 2017 Sep 01;: Authors: Zundler S, Klingberg A, Schillinger D, Fischer S, Neufert C, Atreya I, Gunzer M, Neurath MF Abstract Treatment options for inflammatory bowel diseases such as Crohn’s disease and ulcerative colitis are still limited. The development of novel drugs for optimized therapy depends on translational research, which essentially includes pre-clinical imaging. However, conventional techniques have several limitations including a restricted sample volume that can be analyzed. Here,…

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