A New Look at Familial Risk of Inflammatory Bowel Disease in the Ashkenazi Jewish Population.

Related Articles A New Look at Familial Risk of Inflammatory Bowel Disease in the Ashkenazi Jewish Population. Dig Dis Sci. 2018 Sep 03;: Authors: Schiff ER, Frampton M, Semplici F, Bloom SL, McCartney SA, Vega R, Lovat LB, Wood E, Hart AL, Crespi D, Furman MA, Mann S, Murray CD, Segal AW, Levine AP Abstract BACKGROUND AND AIMS: The inflammatory bowel diseases (IBD) are particularly common among the Ashkenazi Jewish (AJ) population. Population-specific estimates of familial risk are important for counseling; however, relatively small cohorts of AJ IBD patients have…

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Preoperative Misdiagnosis of Intestinal Behçet’s Syndrome as Crohn’s Disease Based on Superficial Colonoscopic Biopsies: Case Report and Systematic Review.

Related Articles Preoperative Misdiagnosis of Intestinal Behçet’s Syndrome as Crohn’s Disease Based on Superficial Colonoscopic Biopsies: Case Report and Systematic Review. Dig Dis Sci. 2018 Aug 28;: Authors: Hakim S, Ramireddy S, Amin M, Gebara S, Cappell MS PMID: 30151660 [PubMed – as supplied by publisher] PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/30151660?dopt=Abstract

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Extensive Disease Subtypes in Adult Patients with Ulcerative Colitis: Non-pancolitis Versus Pancolitis.

Extensive Disease Subtypes in Adult Patients with Ulcerative Colitis: Non-pancolitis Versus Pancolitis. Dig Dis Sci. 2018 Aug 25;: Authors: Shin DS, Cheon JH, Park YE, Park Y, Park SJ, Kim TI, Kim WH Abstract BACKGROUND AND AIM: Few studies have compared pancolitis and non-pancolitis E3 in adult patients with ulcerative colitis (UC). This study aimed to evaluate the natural disease courses and factors affecting outcomes between pancolitis and non-pancolitis E3. METHODS: We retrospectively analyzed 117 patients, including 93 with extensive colitis (E3) and 24 with UC confined to the rectum…

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Correction to: Risk Factors for Clostridium difficile Isolation in Inflammatory Bowel Disease: A Prospective Study.

Related Articles Correction to: Risk Factors for Clostridium difficile Isolation in Inflammatory Bowel Disease: A Prospective Study. Dig Dis Sci. 2018 Aug 22;: Authors: Micic D, Yarur A, Gonsalves A, Rao VL, Broadaway S, Cohen R, Dalal S, Gaetano JN, Glick LR, Hirsch A, Pekow J, Sakuraba A, Walk ST, Rubin DT Abstract The original version of the article unfortunately contained an error in a percentage value in Results section of Abstract. PMID: 30136047 [PubMed – as supplied by publisher] PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/30136047?dopt=Abstract

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IL-17A Promotes Initiation and Development of Intestinal Fibrosis Through EMT.

Related Articles IL-17A Promotes Initiation and Development of Intestinal Fibrosis Through EMT. Dig Dis Sci. 2018 Aug 10;: Authors: Zhang HJ, Zhang YN, Zhou H, Guan L, Li Y, Sun MJ Abstract BACKGROUND: Intestinal fibrosis is a common complication of Crohn’s disease (CD). Its exact mechanism is still unclear, and effective treatments to control or reverse the fibrosis process are unavailable. Epithelial-mesenchymal transition (EMT) may promote intestinal fibrosis by increasing deposition of extracellular matrix protein. IL-17A is a pro-inflammatory cytokine, and it has been shown as a profibrotic factor as…

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Case-Control Study of Inflammatory Bowel Disease Patients with and without Clostridium difficile Infection and Poor Outcomes in Patients Coinfected with C. difficile and Cytomegalovirus.

Case-Control Study of Inflammatory Bowel Disease Patients with and without Clostridium difficile Infection and Poor Outcomes in Patients Coinfected with C. difficile and Cytomegalovirus. Dig Dis Sci. 2018 Aug 09;: Authors: Li Y, Xu H, Xu T, Xiao M, Tang H, Wu D, Tan B, Li J, Yang H, Lv H, Xu Y, Qian J Abstract BACKGROUND AND AIMS: Clostridium difficile infection (CDI) incidence and risk factors in patients with inflammatory bowel disease (IBD) have been extensively studied. However, data describing CDI in Chinese patients with IBD are limited. We…

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Sleep Disturbances Are Commonly Reported Among Patients Presenting to a Gastroenterology Clinic.

Sleep Disturbances Are Commonly Reported Among Patients Presenting to a Gastroenterology Clinic. Dig Dis Sci. 2018 Aug 09;: Authors: Ballou S, Alhassan E, Hon E, Lembo C, Rangan V, Singh P, Hirsch W, Sommers T, Iturrino J, Nee J, Lembo A Abstract BACKGROUND: Poor sleep quality is common among patients with gastrointestinal (GI) disorders. However, few studies have assessed the presence of insomnia or reported circadian preferences and none have directly compared sleep between common GI conditions. AIMS: To compare clinical sleep characteristics in patients presenting to a tertiary care…

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Quercetin Attenuates Adhesion Molecule Expression in Intestinal Microvascular Endothelial Cells by Modulating Multiple Pathways.

Related Articles Quercetin Attenuates Adhesion Molecule Expression in Intestinal Microvascular Endothelial Cells by Modulating Multiple Pathways. Dig Dis Sci. 2018 Aug 04;: Authors: Bian Y, Liu P, Zhong J, Hu Y, Zhuang S, Fan K, Liu Z Abstract BACKGROUND: In inflammatory bowel disease, activation of microvascular endothelial cells and adhesion of immune cells are required for the initiation and maintenance of inflammation. We evaluated the effects and mechanisms of quercetin, a flavone identified in a wide variety of dietary sources, in LPS-induced rat intestinal microvascular endothelial cells (RIMVECs). METHODS: RIMVECs…

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