Lateral pararectal versus transrectal stoma placement for prevention of parastomal herniation.

Related Articles Lateral pararectal versus transrectal stoma placement for prevention of parastomal herniation. Cochrane Database Syst Rev. 2019 Apr 24;4:CD009487 Authors: Hardt J, Meerpohl JJ, Metzendorf MI, Kienle P, Post S, Herrle F Abstract BACKGROUND: A parastomal hernia is defined as an incisional hernia related to a stoma, and belongs to the most common stoma-related complications. Many factors, which are considered to influence the incidence of parastomal herniation, have been investigated. However, it remains unclear whether the enterostomy should be placed through, or lateral to the rectus abdominis muscle, in…

Read More

Adjuvant therapy with antidepressants for the management of inflammatory bowel disease.

Related Articles Adjuvant therapy with antidepressants for the management of inflammatory bowel disease. Cochrane Database Syst Rev. 2019 Apr 12;4:CD012680 Authors: Mikocka-Walus A, Prady SL, Pollok J, Esterman AJ, Gordon AL, Knowles S, Andrews JM Abstract BACKGROUND: Symptoms of anxiety and depression are common in inflammatory bowel disease (IBD). Antidepressants are taken by approximately 30% of people with IBD. However, there are no current guidelines on treating co-morbid anxiety and depression in people with IBD with antidepressants, nor are there clear data on the role of antidepressants in managing physical…

Read More

Biomedical risk assessment as an aid for smoking cessation.

Biomedical risk assessment as an aid for smoking cessation. Cochrane Database Syst Rev. 2019 Mar 26;3:CD004705 Authors: Clair C, Mueller Y, Livingstone-Banks J, Burnand B, Camain JY, Cornuz J, Rège-Walther M, Selby K, Bize R Abstract BACKGROUND: A possible strategy for increasing smoking cessation rates could be to provide smokers with feedback on the current or potential future biomedical effects of smoking using, for example, measurement of exhaled carbon monoxide (CO), lung function, or genetic susceptibility to lung cancer or other diseases. OBJECTIVES: The main objective was to determine the…

Read More

Psychological interventions for parents of children and adolescents with chronic illness.

Psychological interventions for parents of children and adolescents with chronic illness. Cochrane Database Syst Rev. 2019 Mar 18;3:CD009660 Authors: Law E, Fisher E, Eccleston C, Palermo TM Abstract BACKGROUND: Psychological therapies for parents of children and adolescents with chronic illness aim to improve parenting behavior and mental health, child functioning (behavior/disability, mental health, and medical symptoms), and family functioning.This is an updated version of the original Cochrane Review (2012) which was first updated in 2015. OBJECTIVES: To evaluate the efficacy and adverse events of psychological therapies for parents of children…

Read More

Dietary interventions for induction and maintenance of remission in inflammatory bowel disease.

Dietary interventions for induction and maintenance of remission in inflammatory bowel disease. Cochrane Database Syst Rev. 2019 Feb 08;2:CD012839 Authors: Limketkai BN, Iheozor-Ejiofor Z, Gjuladin-Hellon T, Parian A, Matarese LE, Bracewell K, MacDonald JK, Gordon M, Mullin GE Abstract BACKGROUND: Inflammatory bowel disease (IBD), comprised of Crohn’s disease (CD) and ulcerative colitis (UC), is characterized by chronic mucosal inflammation, frequent hospitalizations, adverse health economics, and compromised quality of life. Diet has been hypothesised to influence IBD activity. OBJECTIVES: To evaluate the efficacy and safety of dietary interventions on IBD outcomes.…

Read More

Antibiotics for induction and maintenance of remission in Crohn’s disease.

Related Articles Antibiotics for induction and maintenance of remission in Crohn’s disease. Cochrane Database Syst Rev. 2019 Feb 07;2:CD012730 Authors: Townsend CM, Parker CE, MacDonald JK, Nguyen TM, Jairath V, Feagan BG, Khanna R Abstract BACKGROUND: Several antibiotics have been evaluated in Crohn’s disease (CD), however randomised controlled trials (RCTs) have produced conflicting results. OBJECTIVES: To assess the efficacy and safety of antibiotics for induction and maintenance of remission in CD. SEARCH METHODS: We searched MEDLINE, Embase, CENTRAL, the Cochrane IBD Group Specialized Register and Clinicaltrials.gov database from inception to…

Read More

Fecal transplantation for treatment of inflammatory bowel disease.

Related Articles Fecal transplantation for treatment of inflammatory bowel disease. Cochrane Database Syst Rev. 2018 Nov 13;11:CD012774 Authors: Imdad A, Nicholson MR, Tanner-Smith EE, Zackular JP, Gomez-Duarte OG, Beaulieu DB, Acra S Abstract BACKGROUND: Inflammatory bowel disease (IBD) is a chronic, relapsing disease of the gastrointestinal tract that is thought to be associated with a complex interplay between microbes and the immune system, leading to an abnormal inflammatory response in genetically susceptible individuals. Dysbiosis, characterized by the alteration of the composition of the resident commensal bacteria in a host compared…

Read More

Cannabis for the treatment of Crohn’s disease.

Cannabis for the treatment of Crohn’s disease. Cochrane Database Syst Rev. 2018 Nov 08;11:CD012853 Authors: Kafil TS, Nguyen TM, MacDonald JK, Chande N Abstract BACKGROUND: Crohn’s disease (CD) is a chronic immune-mediated condition of transmural inflammation in the gastrointestinal tract, associated with significant morbidity and decreased quality of life. The endocannabinoid system provides a potential therapeutic target for cannabis and cannabinoids and animal models have shown benefit in decreasing inflammation. However, there is also evidence to suggest transient adverse events such as weakness, dizziness and diarrhea, and an increased risk…

Read More

Cannabis for the treatment of ulcerative colitis.

Cannabis for the treatment of ulcerative colitis. Cochrane Database Syst Rev. 2018 Nov 08;11:CD012954 Authors: Kafil TS, Nguyen TM, MacDonald JK, Chande N Abstract BACKGROUND: Cannabis and cannabinoids are often promoted as treatment for many illnesses and are widely used among patients with ulcerative colitis (UC). Few studies have evaluated the use of these agents in UC. Further, cannabis has potential for adverse events and the long-term consequences of cannabis and cannabinoid use in UC are unknown. OBJECTIVES: To assess the efficacy and safety of cannabis and cannabinoids for the…

Read More

Psychological therapies for the management of chronic and recurrent pain in children and adolescents.

Related Articles Psychological therapies for the management of chronic and recurrent pain in children and adolescents. Cochrane Database Syst Rev. 2018 Sep 29;9:CD003968 Authors: Fisher E, Law E, Dudeney J, Palermo TM, Stewart G, Eccleston C Abstract BACKGROUND: This is an update of the original Cochrane review first published in Issue 1, 2003, and previously updated in 2009, 2012 and 2014. Chronic pain, defined as pain that recurs or persists for more than three months, is common in childhood. Chronic pain can affect nearly every aspect of daily life and…

Read More
<< Go Back