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High Dietary Intake of Specific Fatty Acids Increases Risk of Flares in Patients with Ulcerative Colitis in Remission During Treatment With Aminosalicylates.

High Dietary Intake of Specific Fatty Acids Increases Risk of Flares in Patients with Ulcerative Colitis in Remission During Treatment With Aminosalicylates. Clin Gastroenterol Hepatol. 2017 Jan 18;: Authors: Barnes EL, Nestor M, Onyewadume L, De Silva P, Korzenik JR, DREAM Investigators Abstract BACKGROUND & AIMS: Dietary factors may have a significant role in relapse of disease among patients with ulcerative colitis (UC). However, the relationship between diet and UC is inadequately understood. We analyzed data from the diet’s role in exacerbations of mesalamine maintenance study to determine whether dietary…

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Management of Clostridium difficile Infection in Inflammatory Bowel Disease: Expert Review from the Clinical Practice Updates Committee of the AGA Institute.

Related Articles Management of Clostridium difficile Infection in Inflammatory Bowel Disease: Expert Review from the Clinical Practice Updates Committee of the AGA Institute. Clin Gastroenterol Hepatol. 2017 Feb;15(2):166-174 Authors: Khanna S, Shin A, Kelly CP Abstract The purpose of this expert review is to synthesize the existing evidence on the management of Clostridium difficile infection in patients with underlying inflammatory bowel disease. The evidence reviewed in this article is a summation of relevant scientific publications, expert opinion statements, and current practice guidelines. This review is a summary of expert opinion…

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Risk of Rectal Cancer After Colectomy for Patients With Ulcerative Colitis-a National Cohort Study.

Risk of Rectal Cancer After Colectomy for Patients With Ulcerative Colitis-a National Cohort Study. Clin Gastroenterol Hepatol. 2016 Dec 21;: Authors: Abdalla M, Landerholm K, Andersson P, Andersson RE, Myrelid P Abstract BACKGROUND & AIMS: Patients with ulcerative colitis (UC) have an increased risk of rectal cancer, so reconstruction with an ileal pouch anal anastomosis (IPAA) is generally preferred to an ileo-rectal anastomosis (IRA) after subtotal colectomy. Similarly, completion proctectomy is recommended for patients with ileostomy and diverted rectum, although this approach has been questioned because anti-inflammatory agents might reduce…

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Low Risk of Pneumonia From Pneumocystis jirovecii Infection in Patients With Inflammatory Bowel Disease Receiving Immune Suppression.

Low Risk of Pneumonia From Pneumocystis jirovecii Infection in Patients With Inflammatory Bowel Disease Receiving Immune Suppression. Clin Gastroenterol Hepatol. 2016 Dec 21;: Authors: Cotter TG, Gathaiya N, Catania J, Loftus EV, Tremaine WJ, Baddour LM, Harmsen WS, Zinsmeister AR, Sandborn WJ, Limper AH, Pardi DS Abstract BACKGROUND & AIMS: Use of immunosuppressants and inflammatory bowel disease (IBD) may increase the risk of pneumonia caused by Pneumocystis jirovecii (PJP). We assessed the risk of PJP in a population-based cohort of patients with IBD treated with corticosteroids, immune-suppressive medications, and biologics….

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Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection in Patients with Inflammatory Bowel Disease: A Single Center Experience.

Related Articles Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection in Patients with Inflammatory Bowel Disease: A Single Center Experience. Clin Gastroenterol Hepatol. 2016 Dec 03;: Authors: Chin SM, Sauk J, Mahabamunuge J, Kaplan JL, Hohmann EL, Khalili H PMID: 27923723 [PubMed – as supplied by publisher] PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/27923723?dopt=Abstract

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Incidence, Risk Factors, and Outcomes of Colorectal Cancer in Patients with Ulcerative Colitis with Low-Grade Dysplasia: A Systematic Review and Meta-analysis.

Related Articles Incidence, Risk Factors, and Outcomes of Colorectal Cancer in Patients with Ulcerative Colitis with Low-Grade Dysplasia: A Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. 2016 Dec 01;: Authors: Fumery M, Dulai PS, Gupta S, Prokop LJ, Ramamoorthy S, Sandborn WJ, Singh S Abstract BACKGROUND & AIMS: Little is known about outcomes of patients with ulcerative colitis with low-grade dysplasia (UC-LGD). We estimated the incidence of and risk factors for progression to colorectal cancer (CRC) in cohorts of patients with UC-LGD who underwent surveillance (surveillance cohort), and the prevalence…

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Higher Risk of Hospitalization and Serious Infection Among Patients With Ulcerative Colitis Treated with Adalimumab, Compared with Infliximab, in a Nationwide Study.

Higher Risk of Hospitalization and Serious Infection Among Patients With Ulcerative Colitis Treated with Adalimumab, Compared with Infliximab, in a Nationwide Study. Clin Gastroenterol Hepatol. 2016 Nov 29;: Authors: Singh S, Nyboe Andersen N, Andersson M, Loftus EV, Jess T Abstract BACKGROUND & AIMS: We compared the effectiveness and safety of infliximab and adalimumab in biologic-naïve patients with ulcerative colitis (UC), in a nationwide register-based propensity score-matched study of patients in Denmark. METHODS: We collected data from 1719 adults with UC, 15-75 years old, in Denmark who were treated with…

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Association Between Low Trough Levels of Vedolizumab During Induction Therapy for Inflammatory Bowel DiseasesWith Need for Additional Doses Within 6 months.

Association Between Low Trough Levels of Vedolizumab During Induction Therapy for Inflammatory Bowel DiseasesWith Need for Additional Doses Within 6 months. Clin Gastroenterol Hepatol. 2016 Nov 24;: Authors: Williet N, Boschetti G, Fovet M, Di Bernado T, Claudez P, Del Tedesco E, Jarlot C, Rinaldi L, Berger A, Phelip JM, Flourie B, Nancey S, Paul S, Roblin X Abstract BACKGROUND & AIMS: We investigated whether serum trough levels of vedolizumab, a humanized monoclonal antibody against integrin alpha 4 beta 7, during the induction phase of treatment can determine whether patients…

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