Use of Biologic Therapy by Pregnant Women with Inflammatory Bowel Disease Does Not Affect Infant Response to Vaccines.

Related Articles Use of Biologic Therapy by Pregnant Women with Inflammatory Bowel Disease Does Not Affect Infant Response to Vaccines. Clin Gastroenterol Hepatol. 2017 Sep 01;: Authors: Beaulieu DB, Ananthakrishnan AN, Martin C, Cohen RD, Kane SV, Mahadevan U Abstract BACKGROUND & AIMS: In women with inflammatory bowel diseases (IBD), exposure to immunomodulator or biologic therapy has not been associated with adverse events during pregnancy or outcomes of newborns. We investigated whether exposure of patients to these agents during pregnancy affects serologic responses to vaccines in newborns. METHODS: We collected…

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A Systematic Review for the Development of a Core Outcome Set for Ulcerative Colitis Clinical Trials.

A Systematic Review for the Development of a Core Outcome Set for Ulcerative Colitis Clinical Trials. Clin Gastroenterol Hepatol. 2017 Aug 23;: Authors: Ma C, Panaccione R, Fedorak RN, Parker CE, Nguyen TM, Khanna R, Siegel CA, Peyrin-Biroulet L, D’Haens G, Sandborn WJ, Feagan BG, Jairath V Abstract BACKGROUND AND AIMS: Advances in drug development for ulcerative colitis (UC) have been paralleled by innovations in trial design. Development of a core outcome set (COS) to standardize outcome definitions and reporting in clinical trials is desirable. We aim to systematically review…

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Features of Autoimmune Pancreatitis Associated with Inflammatory Bowel Diseases.

Features of Autoimmune Pancreatitis Associated with Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2017 Aug 03;: Authors: Lorenzo D, Maire F, Stefanescu C, Gornet JM, Seksik P, Serrero M, Bournet B, Marteau P, Amiot A, Laharie D, Trang C, Coffin B, Bellaiche G, Cadiot G, Reenaers C, Racine A, Viennot S, Pauwels A, Bouguen G, Savoye G, Pelletier AL, Pineton de Chambrun G, Lahmek P, Nahon S, Abitbol V, GETAID-AIP study group Abstract BACKGROUND & AIMS: Few people know of autoimmune pancreatitis (AIP), a rare disorder associated with inflammatory bowel diseases…

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‘Patients with Ulcerative Colitis and Primary Sclerosing Cholangitis Frequently Have Subclinical Inflammation in the Proximal Colon’.

Related Articles ‘Patients with Ulcerative Colitis and Primary Sclerosing Cholangitis Frequently Have Subclinical Inflammation in the Proximal Colon’. Clin Gastroenterol Hepatol. 2017 Jul 26;: Authors: Cleveland NK, Rubin DT, Hart J, Weber CR, Meckel K, Tran AL, Aelvoet AS, Pan I, Gonsalves A, Gaetano JN, Williams K, Wroblewski K, Jabri B, Pekow J Abstract BACKGROUND AND AIMS: Primary sclerosing cholangitis (PSC) patients with ulcerative colitis (UC) have a high risk of colonic neoplasia. As histologic inflammation is an independent risk factor for the development of neoplasia, we hypothesized that patients…

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Ectopic pregnancy in women with inflammatory bowel disease – a 22 year nationwide cohort study.

Related Articles Ectopic pregnancy in women with inflammatory bowel disease – a 22 year nationwide cohort study. Clin Gastroenterol Hepatol. 2017 Jul 07;: Authors: de Silva PS, Hansen HH, Wehberg S, Friedman S, Nørgård BM Abstract BACKGROUND & AIMS: Data on early adverse pregnancy outcomes in inflammatory bowel disease (IBD) such as ectopic pregnancy (EP) remain limited. We assessed the risk of EP in pregnancies of Danish women with IBD compared to all other Danish women over a 22-year period. In addition, we examined the disease-specific risk of EP in…

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Inflammatory Bowel Disease and Small Bowel Cancer Risk, Clinical Characteristics, and Histopathology- A Population-based Study.

Related Articles Inflammatory Bowel Disease and Small Bowel Cancer Risk, Clinical Characteristics, and Histopathology- A Population-based Study. Clin Gastroenterol Hepatol. 2017 Jul 07;: Authors: Bojesen RD, Riis LB, Høgdall E, Nielsen OH, Jess T Abstract BACKGROUND & AIMS: Inflammatory bowel disease (IBD) may increase risk of small bowel cancer (SBC). However, little is known of the characteristics and features of IBD-SBC, due to a low number of cases worldwide. We performed a population-based study of IBD and SBC to calculate risk and increase our understanding of clinical characteristics and histopathological…

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Bowel Damage in Patients With Long-term Crohn`s Disease, Assessed by Magnetic Resonance Enterography and the Lemann Index.

Related Articles Bowel Damage in Patients With Long-term Crohn`s Disease, Assessed by Magnetic Resonance Enterography and the Lemann Index. Clin Gastroenterol Hepatol. 2017 Jul 07;: Authors: Lunder AK, Jahnsen J, Bakstad LT, Borthne A, Hov JR, Vatn M, Negård A, IBSEN Study Group Abstract BACKGROUND AND AIMS: Magnetic Resonance Enterography (MRE) is used to evaluate the extent and complications of Crohn’s disease (CD) and has recently been included in a score for bowel damage, the Lemann Index (LI). The long-term outcomes of CD are still uncertain and we aimed to…

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Treatment with Biologic Agents has not Reduced Surgeries among Patients with Crohn’s Disease with Short Bowel Syndrome.

Treatment with Biologic Agents has not Reduced Surgeries among Patients with Crohn’s Disease with Short Bowel Syndrome. Clin Gastroenterol Hepatol. 2017 Jun 27;: Authors: Limketkai BN, Parian AM, Chen PH, Colombel JF Abstract BACKGROUND & AIMS: Little is known about the effects of biologic agents used to treat Crohn’s disease (CD) on its long-term complications, such as short bowel syndrome and intestinal failure (SBS-IF). We evaluated trends in small bowel resections and health care utilization among patients with CD with and without SBS-IF. METHODS: We collected data on the National…

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