A Case of Panenteritis With Massive IgG4-Positive Plasma Cell Infiltration Developed 26 Years After Total Proctocolectomy for Ulcerative Colitis.

Related Articles A Case of Panenteritis With Massive IgG4-Positive Plasma Cell Infiltration Developed 26 Years After Total Proctocolectomy for Ulcerative Colitis. Am J Gastroenterol. 2018 Feb;113(2):173 Authors: Tominaga K, Tsuchiya A, Honda Y, Abe T, Yokoyama J, Umezu H, Terai S PMID: 29467530 [PubMed – in process] PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/29467530?dopt=Abstract

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Editorial: Increasing Incidence of Pediatric Inflammatory Bowel Disease in France: Implications for Etiology, Diagnosis, Prognosis, and Treatment.

Related Articles Editorial: Increasing Incidence of Pediatric Inflammatory Bowel Disease in France: Implications for Etiology, Diagnosis, Prognosis, and Treatment. Am J Gastroenterol. 2018 Feb;113(2):273-275 Authors: Barnes EL, Kappelman MD Abstract The significant increase in pediatric-onset inflammatory bowel disease in recent decades appears to be a global phenomenon, with studies from multiple geographic areas noting an increase in Crohn’s disease (CD) and ulcerative colitis (UC). In this large, population-based cohort from northern France, the rapid increase in pediatric CD and UC from 1988-2011 may be due to multiple potential etiologies including…

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Long-Term Safety of In Utero Exposure to Anti-TNFα Drugs for the Treatment of Inflammatory Bowel Disease: Results from the Multicenter European TEDDY Study.

Long-Term Safety of In Utero Exposure to Anti-TNFα Drugs for the Treatment of Inflammatory Bowel Disease: Results from the Multicenter European TEDDY Study. Am J Gastroenterol. 2018 Feb 20;: Authors: Chaparro M, Verreth A, Lobaton T, Gravito-Soares E, Julsgaard M, Savarino E, Magro F, Avni Biron I, Lopez-Serrano P, Casanova MJ, Gompertz M, Vitor S, Arroyo M, Pugliese D, Zabana Y, Vicente R, Aguas M, Bar-Gil Shitrit A, Gutierrez A, Doherty GA, Fernandez-Salazar L, Martínez Cadilla J, Huguet JM, O’Toole A, Stasi E, Manceñido Marcos N, Villoria A, Karmiris K,…

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Longitudinal impact of IBS-type symptoms on disease activity, healthcare utilization, psychological health, and quality of life in inflammatory bowel disease.

Related Articles Longitudinal impact of IBS-type symptoms on disease activity, healthcare utilization, psychological health, and quality of life in inflammatory bowel disease. Am J Gastroenterol. 2018 Feb 16;: Authors: Gracie DJ, Hamlin PJ, Ford AC Abstract OBJECTIVES: The impact of irritable bowel syndrome (IBS)-type symptoms on the natural history of inflammatory bowel disease (IBD) is uncertain. We aimed to address this in a longitudinal study of secondary care patients. METHODS: Longitudinal disease activity was defined by disease flare, escalation of medical therapy, hospitalization, or intestinal resection. The number of investigations…

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Hyperbaric oxygen therapy is well tolerated and effective for ulcerative colitis patients hospitalized for moderate-severe flares: a phase 2A pilot multi-center, randomized, double-blind, sham-controlled trial.

Related Articles Hyperbaric oxygen therapy is well tolerated and effective for ulcerative colitis patients hospitalized for moderate-severe flares: a phase 2A pilot multi-center, randomized, double-blind, sham-controlled trial. Am J Gastroenterol. 2018 Feb 16;: Authors: Dulai PS, Buckey JC, Raffals LE, Swoger JM, Claus PL, O’Toole K, Ptak JA, Gleeson MW, Widjaja CE, Chang JT, Adler JM, Patel N, Skinner LA, Haren SP, Goldby-Reffner K, Thompson KD, Siegel CA Abstract BACKGROUND: Hyperbaric oxygen therapy (HBOT) markedly increases tissue oxygen delivery. Case series suggest it may have a potential therapeutic benefit in…

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Increased Mortality Rates With Prolonged Corticosteroid Therapy When Compared With Antitumor Necrosis Factor-α-Directed Therapy for Inflammatory Bowel Disease.

Related Articles Increased Mortality Rates With Prolonged Corticosteroid Therapy When Compared With Antitumor Necrosis Factor-α-Directed Therapy for Inflammatory Bowel Disease. Am J Gastroenterol. 2018 Jan 16;: Authors: Lewis JD, Scott FI, Brensinger CM, Roy JA, Osterman MT, Mamtani R, Bewtra M, Chen L, Yun H, Xie F, Curtis JR Abstract OBJECTIVES: Crohn’s disease (CD) and ulcerative colitis (UC) are inflammatory bowel diseases (IBD) that compromise quality of life and may increase mortality. This study compared the mortality risk with prolonged corticosteroid use vs. antitumor necrosis factor-α (anti-TNF) drugs in IBD.…

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Corticosteroid Sparing in Inflammatory Bowel Disease is More Often Achieved in the Immunomodulator and Biological Era-Results from the Dutch Population-Based IBDSL Cohort.

Corticosteroid Sparing in Inflammatory Bowel Disease is More Often Achieved in the Immunomodulator and Biological Era-Results from the Dutch Population-Based IBDSL Cohort. Am J Gastroenterol. 2018 Jan 09;: Authors: Jeuring SFG, Biemans VBC, van den Heuvel TRA, Zeegers MP, Hameeteman WH, Romberg-Camps MJL, Oostenbrug LE, Masclee AAM, Jonkers DMAE, Pierik MJ Abstract OBJECTIVES: Corticosteroid-free remission is an emerging treatment goal in the management of inflammatory bowel disease (IBD). In the population-based Inflammatory Bowel Disease South Limburg cohort, we studied temporal changes in corticosteroid use and assessed the corticosteroid-sparing effects of…

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Utility of Magnetic Resonance Enterography For Small Bowel Endoscopic Healing in Patients With Crohn’s Disease.

Utility of Magnetic Resonance Enterography For Small Bowel Endoscopic Healing in Patients With Crohn’s Disease. Am J Gastroenterol. 2017 Dec 19;: Authors: Takenaka K, Ohtsuka K, Kitazume Y, Matsuoka K, Nagahori M, Fujii T, Saito E, Kimura M, Fujioka T, Watanabe M Abstract OBJECTIVES: Small bowel (SB) endoscopic healing has not been well studied in patients with Crohn’s disease (CD). This study aims to evaluate the utility of magnetic resonance (MR) enterography (MRE) for SB lesions in comparison with balloon-assisted enteroscopy (BAE) findings. METHODS: In total, 139 patients with CD…

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Corrigendum: Surgical Rates for Crohn’s Disease Are Decreasing: A Population-Based Time Trend Analysis and Validation Study.

Corrigendum: Surgical Rates for Crohn’s Disease Are Decreasing: A Population-Based Time Trend Analysis and Validation Study. Am J Gastroenterol. 2017 Dec 19;: Authors: Ma C, Moran GW, Benchimol EI, Targownik LE, Heitman SJ, Hubbard JN, Seow CH, Novak KL, Ghosh S, Panaccione R, Kaplan GG Abstract This corrects the article DOI: 10.1038/ajg.2017.394. PMID: 29257148 [PubMed – as supplied by publisher] PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/29257148?dopt=Abstract

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