The Efficacy of Split-Dose Bowel Preparations for Polyp Detection: A Systematic Review and Meta-Analysis.

The Efficacy of Split-Dose Bowel Preparations for Polyp Detection: A Systematic Review and Meta-Analysis. Am J Gastroenterol. 2019 Mar 11;: Authors: Zawaly K, Rumbolt C, Abou-Setta AM, Neilson C, Rabbani R, Zarychanski R, Singh H Abstract INTRODUCTION: Split-dose bowel preparation leads to superior colon cleansing for colonoscopy. However, the magnitude of benefit in detecting colonic polyps is uncertain. We performed a systematic review to synthesize the data on whether using a split-dose bowel preparation regimen improves the detection of polyps when compared with other dosing methods or regimen products. METHODS:…

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Impact of Obesity on Disease Activity and Patient-Reported Outcomes Measurement Information System (PROMIS) in Inflammatory Bowel Diseases.

Impact of Obesity on Disease Activity and Patient-Reported Outcomes Measurement Information System (PROMIS) in Inflammatory Bowel Diseases. Am J Gastroenterol. 2019 Mar 11;: Authors: Jain A, Nguyen NH, Proudfoot JA, Martin CF, Sandborn WJ, Kappelman MD, Long MD, Singh S Abstract INTRODUCTION: We conducted a cohort study on the impact of obesity on disease activity and Patient-Reported Outcomes Measurement Information System (PROMIS) measures in the inflammatory bowel disease (IBD) Partners cohort. METHODS: We performed a cross-sectional and longitudinal study within IBD Partners, an internet-based cohort of >15,000 patients living with…

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A Novel Patient-Reported Outcome-Based Evaluation (PROBE) of Quality of Life in Patients With Inflammatory Bowel Disease.

A Novel Patient-Reported Outcome-Based Evaluation (PROBE) of Quality of Life in Patients With Inflammatory Bowel Disease. Am J Gastroenterol. 2019 Mar 01;: Authors: Barnes EL, Kappelman MD, Long MD, Evon DM, Martin CF, Sandler RS Abstract OBJECTIVES: There is increased interest in measuring patient-reported outcomes (PROs) such as quality of life (QoL) among patients with inflammatory bowel disease (IBD). We aimed to create and validate a new measure of QoL to assess the psychosocial burden of IBD using publicly available assessment tools. METHODS: Using the Crohn’s & Colitis Foundation’s IBD…

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Continuing Medical Education Questions: March 2019.

Continuing Medical Education Questions: March 2019. Am J Gastroenterol. 2019 Mar;114(3):381 Authors: Veerappan GR Abstract To receive CME/MOC credit for this activity, please go to: http://acgjournalcme.gi.org/Article Title: ACG Clinical Guideline: Ulcerative Colitis in Adults. PMID: 30839391 [PubMed – in process] PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/30839391?dopt=Abstract

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ACG Clinical Guideline: Ulcerative Colitis in Adults.

ACG Clinical Guideline: Ulcerative Colitis in Adults. Am J Gastroenterol. 2019 Feb 21;: Authors: Rubin DT, Ananthakrishnan AN, Siegel CA, Sauer BG, Long MD Abstract Ulcerative colitis (UC) is an idiopathic inflammatory disorder. These guidelines indicate the preferred approach to the management of adults with UC and represent the official practice recommendations of the American College of Gastroenterology. The scientific evidence for these guidelines was evaluated using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) process. In instances where the evidence was not appropriate for GRADE, but there was…

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ACG Clinical Guideline: Ulcerative Colitis in Adults.

ACG Clinical Guideline: Ulcerative Colitis in Adults. Am J Gastroenterol. 2019 Mar;114(3):384-413 Authors: Rubin DT, Ananthakrishnan AN, Siegel CA, Sauer BG, Long MD Abstract Ulcerative colitis (UC) is an idiopathic inflammatory disorder. These guidelines indicate the preferred approach to the management of adults with UC and represent the official practice recommendations of the American College of Gastroenterology. The scientific evidence for these guidelines was evaluated using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) process. In instances where the evidence was not appropriate for GRADE, but there was consensus…

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Placing Value on Telemedicine for Inflammatory Bowel Disease.

Placing Value on Telemedicine for Inflammatory Bowel Disease. Am J Gastroenterol. 2019 Jan 30;: Authors: Siegel CA Abstract Telemedicine can take a number of forms. A popular approach is the use of telemonitoring, which takes advantage of available technology to follow patients remotely. Cross and colleagues present the results of a well-done randomized controlled trial to assess the impact of a telemonitoring program for patients with inflammatory bowel disease. They did not show a difference in disease activity, but this study leads us to question whether we know the appropriate…

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Surveillance Colonoscopy for Ulcerative Colitis-Associated Colorectal Cancer Offers Better Overall Survival in Real-World Surgically Resected Cases.

Surveillance Colonoscopy for Ulcerative Colitis-Associated Colorectal Cancer Offers Better Overall Survival in Real-World Surgically Resected Cases. Am J Gastroenterol. 2019 Feb 08;: Authors: Hata K, Anzai H, Ikeuchi H, Futami K, Fukushima K, Sugita A, Uchino M, Higashi D, Itabashi M, Watanabe K, Koganei K, Araki T, Kimura H, Mizushima T, Ueda T, Ishihara S, Suzuki Y, Research Group for Intractable Inflammatory Bowel Disease of the Ministry of Health, Labour and Welfare of Japan (RGIBD) Abstract OBJECTIVES: To determine the effectiveness of surveillance colonoscopy (SC) and optimize its use by…

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A High Prevalence of Gastrointestinal Manifestations in Common Variable Immunodeficiency.

A High Prevalence of Gastrointestinal Manifestations in Common Variable Immunodeficiency. Am J Gastroenterol. 2019 Feb 08;: Authors: Pikkarainen S, Martelius T, Ristimäki A, Siitonen S, Seppänen MRJ, Färkkilä M Abstract OBJECTIVES: Common variable immunodeficiency (CVID) is associated with a spectrum of autoimmune complications. We studied the prevalence of gastrointestinal (GI) manifestations and infections in patients with CVID. METHODS: Complete clinical data of 132 Finnish patients with CVID (106 probable and 26 possible CVID) followed up between 2007 and 2016 were collected to a structured database. Data on endoscopies, histology, and…

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Development and Validation of a Novel Diagnostic Nomogram to Differentiate Between Intestinal Tuberculosis and Crohn’s Disease: A 6-year Prospective Multicenter Study.

Development and Validation of a Novel Diagnostic Nomogram to Differentiate Between Intestinal Tuberculosis and Crohn’s Disease: A 6-year Prospective Multicenter Study. Am J Gastroenterol. 2019 Feb 07;: Authors: He Y, Zhu Z, Chen Y, Chen F, Wang Y, Ouyang C, Yang H, Huang M, Zhuang X, Mao R, Ben-Horin S, Wu X, Ouyang Q, Qian J, Lu N, Hu P, Chen M Abstract OBJECTIVES: Differentiating Crohn’s disease (CD) from intestinal tuberculosis (ITB) remains a diagnostic challenge. Misdiagnosis carries potential grave implications. We aimed to develop and validate a novel diagnostic…

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