The outcome of ulcerative colitis patients undergoing pouch surgery is determined by pre-surgical factors.

The outcome of ulcerative colitis patients undergoing pouch surgery is determined by pre-surgical factors. Aliment Pharmacol Ther. 2017 Jun 30;: Authors: Yanai H, Ben-Shachar S, Mlynarsky L, Godny L, Leshno M, Tulchinsky H, Dotan I Abstract BACKGROUND: Pouch surgery, a common intervention for ulcerative colitis (UC) complications, is often associated with the development of pouchitis. AIM: To identify predictors of pouch outcome in a cohort of patients with UC. METHODS: We conducted a retrospective unmatched case-cohort study in a tertiary IBD referral centre. Adult patients with UC were classified into…

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The development of a magnetic resonance imaging index for fistulising Crohn’s disease.

The development of a magnetic resonance imaging index for fistulising Crohn’s disease. Aliment Pharmacol Ther. 2017 Jun 27;: Authors: Samaan MA, Puylaert CAJ, Levesque BG, Zou GY, Stitt L, Taylor SA, Shackelton LM, Vandervoort MK, Khanna R, Santillan C, Rimola J, Hindryckx P, Nio CY, Sandborn WJ, D’Haens G, Feagan BG, Jairath V, Stoker J Abstract BACKGROUND: Magnetic resonance imaging (MRI) is the gold standard for assessment of perianal fistulising Crohn’s disease (CD). The Van Assche index is the most commonly used MRI fistula index. AIMS: To assess the reliability…

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Systematic review with meta-analysis: the efficacy of probiotics in inflammatory bowel disease.

Systematic review with meta-analysis: the efficacy of probiotics in inflammatory bowel disease. Aliment Pharmacol Ther. 2017 Jun 27;: Authors: Derwa Y, Gracie DJ, Hamlin PJ, Ford AC Abstract BACKGROUND: Ulcerative colitis (UC) and Crohn’s disease (CD) are inflammatory bowel diseases (IBD). Evidence implicates disturbances of the gastrointestinal microbiota in their pathogenesis. AIM: To perform a systematic review and meta-analysis to examine the efficacy of probiotics in IBD. METHODS: MEDLINE, EMBASE, and the Cochrane Controlled Trials Register were searched (until November 2016). Eligible randomised controlled trials (RCTs) recruited adults with UC…

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