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Predictors of vitamin D deficiency in inflammatory bowel disease and health: A Mississippi perspective.

Related Articles Predictors of vitamin D deficiency in inflammatory bowel disease and health: A Mississippi perspective. World J Gastroenterol. 2017 Jan 28;23(4):638-645 Authors: Pallav K, Riche D, May WL, Sanchez P, Gupta NK Abstract AIM: To identify the predictors of vitamin D deficiency in patients with and without inflammatory bowel disease (IBD). METHODS: Patients with ulcerative colitis (UC) or Crohn’s disease (CD) related diagnostic codes who received medical care at University of Mississippi Medical Center between July 2012 and 2015 were identified. After thorough chart review, we identified patients with…

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Impact of High-Dose Vitamin D3 Supplementation in Patients with Crohn’s Disease in Remission: A Pilot Randomized Double-Blind Controlled Study.

Impact of High-Dose Vitamin D3 Supplementation in Patients with Crohn’s Disease in Remission: A Pilot Randomized Double-Blind Controlled Study. Dig Dis Sci. 2016 Dec 14; Authors: Narula N, Cooray M, Anglin R, Muqtadir Z, Narula A, Marshall JK Abstract AIM: To assess the tolerability and efficacy of high-dose vitamin D3 in patients with Crohn’s disease (CD). METHODS: This was a randomized, double-blind placebo-controlled trial of high-dose vitamin D3 at 10,000 IU daily (n = 18) compared to 1000 IU daily (n = 16) for 12 months in patients with CD in remission. The primary outcome was change…

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Lower Vitamin D Status May Explain why African Americans Have Poorer Outcomes than Non-African Americans After Surgery for Crohn’s Disease.

Related Articles Lower Vitamin D Status May Explain why African Americans Have Poorer Outcomes than Non-African Americans After Surgery for Crohn’s Disease. J Crohns Colitis. 2016 Oct 20;: Authors: Grant WB PMID: 27797920 [PubMed – as supplied by publisher] PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/27797920?dopt=Abstract

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Synergistic inhibitory effect of cyclosporin A and vitamin D derivatives on T-lymphocyte proliferation in active ulcerative colitis.

Related Articles Synergistic inhibitory effect of cyclosporin A and vitamin D derivatives on T-lymphocyte proliferation in active ulcerative colitis. Am J Gastroenterol. 2002 Mar;97(3):679-89 Authors: Stio M, Treves C, Celli A, Tarantino O, d’Albasio G, Bonanomi AG Abstract OBJECTIVE: 1,25-Dihydroxyvitamin D3 [1,25(OH)2D3], the hormonal active form of vitamin D3, could represent a potentially therapeutic agent in autoimmune diseases. Cyclosporin A (CsA) shows immunoregulatory properties, which, in many respects, seem to be similar to those of 1,25(OH)2D3. Our aim was to investigate the possible synergistic effect exerted by CsA in combination…

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Treatment of vitamin D deficiency due to Crohn’s disease with tanning bed ultraviolet B radiation.

Related Articles Treatment of vitamin D deficiency due to Crohn’s disease with tanning bed ultraviolet B radiation. Gastroenterology. 2001 Dec;121(6):1485-8 Authors: Koutkia P, Lu Z, Chen TC, Holick MF Abstract In Crohn’s disease, severe skeletal demineralization, secondary hyperparathyroidism, and muscle weakness can occur. This may be caused by impaired vitamin D absorption, resulting from extensive intestinal disease and resection of duodenum and jejunum, where vitamin D is absorbed. We report a 57-year-old woman with a long history of Crohn’s disease and short-bowel syndrome who had only 2 feet of small…

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Vitamin D receptor gene polymorphism: association with Crohn’s disease susceptibility.

Related Articles Vitamin D receptor gene polymorphism: association with Crohn’s disease susceptibility. Gut. 2000 Aug;47(2):211-4 Authors: Simmons JD, Mullighan C, Welsh KI, Jewell DP Abstract BACKGROUND: The vitamin D receptor (VDR) gene represents a strong positional candidate susceptibility gene for inflammatory bowel disease (IBD). The VDR gene maps to a region on chromosome 12 that has been shown to be linked to IBD by genome screening techniques. It is the cellular receptor for 1,25(OH)(2) vitamin D(3) (calcitriol) which has a wide range of different regulatory effects on the immune system….

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Bone disease in vitamin D-deficient patients with Crohn’s disease.

Related Articles Bone disease in vitamin D-deficient patients with Crohn’s disease. Dig Dis Sci. 1989 Jul;34(7):1094-9 Authors: Vogelsang H, Ferenci P, Woloszczuk W, Resch H, Herold C, Frotz S, Gangl A Abstract Vitamin D deficiency is frequently observed in patients with Crohn’s disease and may be associated with an increased risk of development of metabolic bone disease. To estimate the incidence of metabolic bone disease by noninvasive methods, 31 patients (17-75 years old) with Crohn’s disease and low 25-hydroxyvitamin D (25-OHD) levels in winter were investigated in the following summer…

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Vitamin D status in Crohn’s disease: association with nutrition and disease activity.

Related Articles Vitamin D status in Crohn’s disease: association with nutrition and disease activity. Gut. 1985 Nov;26(11):1197-203 Authors: Harries AD, Brown R, Heatley RV, Williams LA, Woodhead S, Rhodes J Abstract Forty patients with Crohn’s disease were divided into undernourished (18) and well nourished (22) groups depending on whether their midarm circumference was below or above 90% of the ideal standard. Plasma 25-(OH)D3 and the dihydroxylated metabolites, 24,25-(OH)2D3 and 1,25-(OH)2D3 were measured in the summer. Results were related to clinical and biochemical parameters and also compared with results from patients…

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