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Dietary Therapy with the Crohn’s Disease Exclusion Diet is a Successful Strategy for Induction of Remission in Children and Adults Failing Biological Therapy.

Dietary Therapy with the Crohn’s Disease Exclusion Diet is a Successful Strategy for Induction of Remission in Children and Adults Failing Biological Therapy. J Crohns Colitis. 2017 May 19;: Authors: Sigall Boneh R, Sarbagili-Shabat C, Yanai H, Chermesh I, Ben Avraham S, Boaz M, Levine A Abstract Background: Loss of response (LoR) to biologics in Crohn’s disease (CD) is a significant clinical problem. Dietary therapy as a treatment strategy in this setting has not been previously reported. We report the use of dietary strategies using enteral nutrition coupled with the…

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Diet and microbiota in inflammatory bowel disease: The gut in disharmony.

Related Articles Diet and microbiota in inflammatory bowel disease: The gut in disharmony. World J Gastroenterol. 2017 Mar 28;23(12):2124-2140 Authors: Rapozo DC, Bernardazzi C, de Souza HS Abstract Bacterial colonization of the gut shapes both the local and the systemic immune response and is implicated in the modulation of immunity in both healthy and disease states. Recently, quantitative and qualitative changes in the composition of the gut microbiota have been detected in Crohn’s disease and ulcerative colitis, reinforcing the hypothesis of dysbiosis as a relevant mechanism underlying inflammatory bowel disease…

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Iron Supplements Modulate Colon Microbiota Composition and Potentiate the Protective Effects of Probiotics in Dextran Sodium Sulfate-induced Colitis.

Iron Supplements Modulate Colon Microbiota Composition and Potentiate the Protective Effects of Probiotics in Dextran Sodium Sulfate-induced Colitis. Inflamm Bowel Dis. 2017 Mar 31;: Authors: Constante M, Fragoso G, Lupien-Meilleur J, Calvé A, Santos MM Abstract BACKGROUND: Iron is an important nutrient for both the host and colonizing bacteria. Oral iron supplementation may impact the composition of the microbiota and can be particularly damaging to patients suffering from inflammatory bowel disease (IBD). However, patients with IBD may require iron supplementation to treat their anemia. METHODS: We fed mice with diets…

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Use of the low-FODMAP diet in inflammatory bowel disease.

Use of the low-FODMAP diet in inflammatory bowel disease. J Gastroenterol Hepatol. 2017 Mar;32 Suppl 1:40-42 Authors: Gibson PR Abstract Irritable bowel syndrome (IBS)-like symptoms are not uncommon in patients with quiescent inflammatory bowel disease (IBD). While gluten-free diet is applied by patients, there are no reported interventional studies. The low-FODMAP diet, on the other hand, has efficacy similar to that seen in patients with IBS in three unblinded or observational studies of IBD cohorts who had well-controlled inflammatory disease and in one small randomized cross-over study. FODMAP intake by…

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Using eHealth strategies in delivering dietary and other therapies in patients with irritable bowel syndrome and inflammatory bowel disease.

Using eHealth strategies in delivering dietary and other therapies in patients with irritable bowel syndrome and inflammatory bowel disease. J Gastroenterol Hepatol. 2017 Mar;32 Suppl 1:27-31 Authors: Ankersen DV, Carlsen K, Marker D, Munkholm P, Burisch J Abstract Health-care systems around the world are facing increasing costs. Non-adherent, chronically ill patients are one such expense incurred by health-care providers. Web-based home-monitoring of patients-or eHealth-has been shown to increase adherence to medical therapy, facilitate contact between patients and health-care professionals, and reduce time to remission for patients with inflammatory bowel disease…

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Evaluating clinical, dietary and psychological risk factors for relapse of ulcerative colitis in clinical, endoscopic and histological remission.

Evaluating clinical, dietary and psychological risk factors for relapse of ulcerative colitis in clinical, endoscopic and histological remission. J Gastroenterol Hepatol. 2017 Feb 21;: Authors: Dhingra R, Kedia S, Venigalla PM, Kumar S, Singh N, Bopanna S, Singla V, Choudhury BN, Verma P, Tiwari V, Datta Gupta S, Makharia G, Ahuja V Abstract BACKGROUND: The literature on possible factors that could trigger a relapse in patients with ulcerative colitis (UC) in clinical, endoscopic and histological remission on long term follow up is scarce. AIM: To determine the relapse rate in…

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O-013 Dietary Emulsifiers Directly Impact the Human Gut Microbiota Increasing Its Pro-inflammatory Potential and Ability to Induce Intestinal Inflammation.

O-013 Dietary Emulsifiers Directly Impact the Human Gut Microbiota Increasing Its Pro-inflammatory Potential and Ability to Induce Intestinal Inflammation. Inflamm Bowel Dis. 2017 Feb;23 Suppl 1:S5 Authors: Chassaing B, Van de Wiele T, Gewirtz A Abstract BACKGROUND: The intestinal microbiota plays a central role in the development of many chronic inflammatory diseases including inflammatory bowel disease. Accordingly, we recently demonstrated that administration of substances that alter microbiota composition, including the dietary emulsifiers polysorbate 80 (P80) and carboxymethylcellulose (CMC), promotes such inflammatory disorders. However, because inflammation itself impacts microbiota composition, it…

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High Dietary Intake of Specific Fatty Acids Increases Risk of Flares in Patients with Ulcerative Colitis in Remission During Treatment With Aminosalicylates.

High Dietary Intake of Specific Fatty Acids Increases Risk of Flares in Patients with Ulcerative Colitis in Remission During Treatment With Aminosalicylates. Clin Gastroenterol Hepatol. 2017 Jan 18;: Authors: Barnes EL, Nestor M, Onyewadume L, De Silva P, Korzenik JR, DREAM Investigators Abstract BACKGROUND & AIMS: Dietary factors may have a significant role in relapse of disease among patients with ulcerative colitis (UC). However, the relationship between diet and UC is inadequately understood. We analyzed data from the diet’s role in exacerbations of mesalamine maintenance study to determine whether dietary…

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Diet to the Rescue: Cessation of Pharmacotherapy After Initiation of Exclusive Enteral Nutrition (EEN) Followed by Strict and Liberalized Specific Carbohydrate Diet (SCD) in Crohn’s Disease.

Diet to the Rescue: Cessation of Pharmacotherapy After Initiation of Exclusive Enteral Nutrition (EEN) Followed by Strict and Liberalized Specific Carbohydrate Diet (SCD) in Crohn’s Disease. Dig Dis Sci. 2017 Jan 13;: Authors: Nakayuenyongsuk W, Christofferson M, Nguyen K, Burgis J, Park KT PMID: 28084605 [PubMed – as supplied by publisher] PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/28084605?dopt=Abstract

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