Food Exclusion Based on IgG Antibodies Alleviates Symptoms in Ulcerative Colitis: A Prospective Study.

Food Exclusion Based on IgG Antibodies Alleviates Symptoms in Ulcerative Colitis: A Prospective Study. Inflamm Bowel Dis. 2018 May 16;: Authors: Jian L, Anqi H, Gang L, Litian W, Yanyan X, Mengdi W, Tong L Abstract Background: Most patients with ulcerative colitis (UC) rely predominantly on medication for disease control. Diet interventions can reduce pharmaceutical expenditures and prolong remission. We designed a prospective study to evaluate whether an immunoglobulin G (IgG)-guided exclusion diet would improve symptoms and quality of life (QoL) in patients with UC. Methods: The 6-month diet intervention…

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Dietary Magnesium Alleviates Experimental Murine Colitis Through Upregulation of the Transient Receptor Potential Melastatin 6 Channel.

Dietary Magnesium Alleviates Experimental Murine Colitis Through Upregulation of the Transient Receptor Potential Melastatin 6 Channel. Inflamm Bowel Dis. 2018 May 18;: Authors: Trapani V, Petito V, Di Agostini A, Arduini D, Hamersma W, Pietropaolo G, Luongo F, Arena V, Stigliano E, Lopetuso LR, Gasbarrini A, Wolf FI, Scaldaferri F Abstract Background: Magnesium (Mg) is essential for human health and is absorbed mainly in the intestine. In view of the likely occurrence of an Mg deficit in inflammatory bowel disease (IBD) and the documented role of Mg in modulating inflammation,…

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A Single Nucleotide Polymorphism in the Vitamin D Receptor Gene Is Associated With Decreased Levels of the Protein and a Penetrating Pattern in Crohn’s Disease.

A Single Nucleotide Polymorphism in the Vitamin D Receptor Gene Is Associated With Decreased Levels of the Protein and a Penetrating Pattern in Crohn’s Disease. Inflamm Bowel Dis. 2018 May 18;: Authors: Gisbert-Ferrándiz L, Salvador P, Ortiz-Masiá D, Macías-Ceja DC, Orden S, Esplugues JV, Calatayud S, Hinojosa J, Barrachina MD, Hernández C Abstract Background: Vitamin D signaling modulates inflammation through the vitamin D receptor (VDR). The synonymous single nucleotide polymorphism (SNP) rs731236, located in the VDR gene, has been associated with a higher risk of Crohn’s disease (CD). We analyzed…

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Evolving role of diet in the pathogenesis and treatment of inflammatory bowel diseases.

Related Articles Evolving role of diet in the pathogenesis and treatment of inflammatory bowel diseases. Gut. 2018 May 18;: Authors: Levine A, Sigall Boneh R, Wine E Abstract Recent advances in basic and clinical science over the last 3 years have dramatically altered our appreciation of the role of diet in inflammatory bowel diseases (IBD). The marked increase in incidence of these diseases along with the important role of non-genetic susceptibility among patients with IBD has highlighted that these diseases have a strong environmental component. Progress in the field of microbiome…

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The effect of vitamin D on intestinal inflammation and faecal microbiota in patients with ulcerative colitis.

Related Articles The effect of vitamin D on intestinal inflammation and faecal microbiota in patients with ulcerative colitis. J Crohns Colitis. 2018 May 03;: Authors: Garg M, Hendy P, Ding JN, Shaw S, Hold G, Hart A Abstract Background and Aims: There is evidence vitamin D may be immunomodulatory and alter faecal microbiota, but results from clinical studies in humans to date have been inconclusive. This study aimed to assess the effect of vitamin D replacement in vitamin D deficient patients with and without ulcerative colitis (UC) on inflammation and…

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The Association of Diet and Exercise With Body Composition in Pediatric Crohn’s Disease.

Related Articles The Association of Diet and Exercise With Body Composition in Pediatric Crohn’s Disease. Inflamm Bowel Dis. 2018 Apr 27;: Authors: Lee D, Lewis JD, Shults J, Baldassano RN, Long J, Herskovitz R, Zemel B, Leonard MB Abstract Background: In pediatric Crohn’s disease, fat mass improves over time with treatment, but lean mass deficits persist. This observational study of the associations of physical activity and dietary intake with lean mass and muscle strength in children with Crohn’s disease was ancillary to a previously reported randomized clinical trial of an…

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Diet and Anthropometrics of Children With Inflammatory Bowel Disease: A Comparison With the General Population.

Related Articles Diet and Anthropometrics of Children With Inflammatory Bowel Disease: A Comparison With the General Population. Inflamm Bowel Dis. 2018 Apr 25;: Authors: Diederen K, Krom H, Koole JCD, Benninga MA, Kindermann A Abstract Background: There is a lack of knowledge regarding the diet of children with inflammatory bowel disease (IBD). Therefore, we investigated dietary intake in pediatric IBD compared to the general population and assessed anthropometrics and food avoidance. Methods: In this cross-sectional cohort study, patients younger than 18 years with IBD were included (2014-2017). Dietary intake (total…

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Dietary Supplementation with a Bacillus Superoxide Dismutase Protects Against γ-Radiation-induced Oxidative Stress and Ameliorates Dextran Sulfate Sodium-induced Ulcerative Colitis in Mice.

Dietary Supplementation with a Bacillus Superoxide Dismutase Protects Against γ-Radiation-induced Oxidative Stress and Ameliorates Dextran Sulfate Sodium-induced Ulcerative Colitis in Mice. J Crohns Colitis. 2018 Mar 14;: Authors: Kang JE, Kim HD, Park SY, Pan JG, Kim JH, Yum DY Abstract Background and Aims: Commercial superoxide dismutase (SOD) is derived from melon extract and has a potential as a dietary supplement due to its beneficial anti-oxidative effects. We aimed to improve the productivity of SOD compared with plant SOD by using a generally-regarded-as-safe (GRAS) microorganism, Bacillus amyloliquefaciens, and assess its…

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