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Development and Validation of a Questionnaire to Assess the Quality of Life in Patients with Inflammatory Bowel Disease in Mainland China.

Development and Validation of a Questionnaire to Assess the Quality of Life in Patients with Inflammatory Bowel Disease in Mainland China. Inflamm Bowel Dis. 2017 Jan 26;: Authors: Ruan J, Chen Y, Zhou Y Abstract BACKGROUND: Inflammatory bowel disease (IBD) affects the quality of patients’ life in many ways. The aim of this study was to develop and validate a mainland Chinese version of IBD quality-of-life questionnaire for ulcerative colitis (UC) and Crohn’s disease (CD). METHODS: A draft questionnaire containing 30 items was generated from a descriptive qualitative study, literature…

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Estimation of quality of life in Cypriot patients with inflammatory bowel disease.

Related Articles Estimation of quality of life in Cypriot patients with inflammatory bowel disease. World J Gastroenterol. 2017 Jan 07;23(1):121-126 Authors: Tsoukka M, Jelastopulu E, Lavranos G, Charalambous G Abstract AIM: To investigate the health-related quality of life (HRQoL) of patients suffering with idiopathic inflammatory bowel disease (IBD). METHODS: The Greek validated version of the Short Inflammatory Bowel Disease Questionnaire was used for evaluating the quality of life of IBD patients. The questionnaire was distributed to 100 consecutive patients suffering from IBD and presenting for a clinic appointment at the…

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Older Age- and Health-related Quality of Life in Inflammatory Bowel Diseases.

Older Age- and Health-related Quality of Life in Inflammatory Bowel Diseases. Inflamm Bowel Dis. 2017 Jan 06;: Authors: Velonias G, Conway G, Andrews E, Garber JJ, Khalili H, Yajnik V, Ananthakrishnan AN Abstract BACKGROUND: The burden of inflammatory bowel disease (IBD) in the older population is increasing. Older-onset disease is associated with reduced use of immunosuppressive medications. In addition, older patients may be more vulnerable to the effect of disease-related symptoms and consequently may experience worse health-related quality of life (HRQoL) compared with younger patients. METHODS: This prospective study included…

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Sex Is Associated with Adalimumab Side Effects and Drug Survival in Patients with Crohn’s Disease.

Sex Is Associated with Adalimumab Side Effects and Drug Survival in Patients with Crohn’s Disease. Inflamm Bowel Dis. 2017 Jan;23(1):75-81 Authors: Lie MR, Kreijne JE, van der Woude CJ Abstract BACKGROUND: Adalimumab (ADA) is an effective treatment for Crohn’s disease (CD). In rheumatology, sex differences concerning the response to ADA therapy have been described. However, such differences have not yet been reported for patients with CD. As such, the aim of this study was to compare ADA treatment outcomes in male and female patients with CD. METHODS: A clinical cohort…

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The contribution of clinical and psychosocial factors to fatigue in 182 patients with inflammatory bowel disease: a cross-sectional study.

Related Articles The contribution of clinical and psychosocial factors to fatigue in 182 patients with inflammatory bowel disease: a cross-sectional study. Aliment Pharmacol Ther. 2016 Nov 20;: Authors: Artom M, Czuber-Dochan W, Sturt J, Murrells T, Norton C Abstract BACKGROUND: Fatigue is a frequently reported and predominant symptom experienced by patients with inflammatory bowel disease (IBD) and its impact has been associated with poorer quality of life (QoL). The complex interplay between disease-related variables and potentially modifiable psychosocial factors in IBD-fatigue has yet to be unravelled. AIM: To evaluate the…

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Effects of vedolizumab on health-related quality of life in patients with ulcerative colitis: results from the randomised GEMINI 1 trial.

Related Articles Effects of vedolizumab on health-related quality of life in patients with ulcerative colitis: results from the randomised GEMINI 1 trial. Aliment Pharmacol Ther. 2016 Nov 17;: Authors: Feagan BG, Patel H, Colombel JF, Rubin DT, James A, Mody R, Lasch K Abstract BACKGROUND: Health-related quality of life (HRQL) is often diminished in patients with ulcerative colitis. AIM: To evaluate the effects of vedolizumab on HRQL in patients with ulcerative colitis. METHODS: Using maintenance phase data from the GEMINI 1 study, an analysis of covariance model was used to…

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Fluoxetine for Maintenance of Remission and to Improve Quality of Life in Patients with Crohn’s Disease: a Pilot Randomized Placebo-Controlled Trial.

Related Articles Fluoxetine for Maintenance of Remission and to Improve Quality of Life in Patients with Crohn’s Disease: a Pilot Randomized Placebo-Controlled Trial. J Crohns Colitis. 2016 Sep 23;: Authors: Mikocka-Walus A, Hughes PA, Bampton P, Gordon A, Campaniello MA, Mavrangelos C, Stewart BJ, Esterman A, Andrews JM Abstract BACKGROUND AND AIMS: Previous studies have shown that antidepressants reduce inflammation in animal models of colitis. The present trial aimed to examine whether fluoxetine added to standard therapy for Crohn’s disease [CD] maintained remission, improved quality of life [QoL] and/or mental…

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Etiology and Treatment of Pain and Psychosocial Issues in Patients with Inflammatory Bowel Diseases.

Related Articles Etiology and Treatment of Pain and Psychosocial Issues in Patients with Inflammatory Bowel Diseases. Gastroenterology. 2016 Nov 2;: Authors: Regueiro M, Greer JB, Szigethy E Abstract There is increasing evidence that brain-gut interactions are altered during development of inflammatory bowel diseases (IBD). Understanding the relationship between the neurobiology, psychological symptoms, and social ramifications of IBD can guide comprehensive care for the whole patient. The most common psychological conditions in patients with IBD are chronic abdominal pain, anxiety, and depression. We review the evidence-based data and rates of these…

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Study of sexual, urinary, and fecal function in females following restorative proctocolectomy.

Related Articles Study of sexual, urinary, and fecal function in females following restorative proctocolectomy. Inflamm Bowel Dis. 2012 Sep;18(9):1601-7 Authors: Cornish J, Wooding K, Tan E, Nicholls RJ, Clark SK, Tekkis PP Abstract BACKGROUND: The aim was to investigate quality of life, sexual, fecal, and urinary function in females undergoing restorative proctocolectomy (RPC). METHODS: A prospective case-control study was performed in two tertiary centers. Controls were females with ulcerative colitis, without a stoma or RPC. Validated questionnaires (SF-36, Female sexual function index, King’s questionnaire, and the Wexner scale) were administered…

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