Anti-tumor necrosis factor therapy decreases the risk of initial intestinal surgery after diagnosis of Crohn’s disease of inflammatory type.

Anti-tumor necrosis factor therapy decreases the risk of initial intestinal surgery after diagnosis of Crohn’s disease of inflammatory type. J Gastroenterol. 2018 Sep 22;: Authors: Nagata Y, Esaki M, Moriyama T, Hirano A, Umeno J, Maehata Y, Torisu T, Matsumoto T, Kitazono T Abstract BACKGROUND: Anti-tumor necrosis factor (TNF) therapy induces and maintains clinical remission in patients with Crohn’s disease (CD). However, the effect of anti-TNF therapy on the natural course of CD remains controversial. We aimed to investigate the effect of anti-TNF therapy on the initial intestinal surgery for…

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Outcomes of Endoscopic Balloon Dilation vs Surgical Resection for Primary Ileocolic Strictures in Patients With Crohn’s Disease.

Outcomes of Endoscopic Balloon Dilation vs Surgical Resection for Primary Ileocolic Strictures in Patients With Crohn’s Disease. Clin Gastroenterol Hepatol. 2018 Oct;16(10):1682-1683 Authors: Li JD, Xu XF, Xing H PMID: 30243356 [PubMed – in process] PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/30243356?dopt=Abstract

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Review article: the relationship between obesity, bariatric surgery, and inflammatory bowel disease.

Review article: the relationship between obesity, bariatric surgery, and inflammatory bowel disease. Aliment Pharmacol Ther. 2018 Sep 04;: Authors: Cañete F, Mañosa M, Clos A, Cabré E, Domènech E Abstract BACKGROUND: The convoluted relationship between obesity, bariatric surgery and inflammatory bowel disease (IBD) is of increasing interest. AIM: To analyse evidence regarding the role of bariatric surgery in the development of de novo IBD and its impact on clinical outcomes and safety in patients with established IBD. METHODS: A PubMed/Medline search was performed to identify studies reporting the development of…

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Bowel wall healing assessed using magnetic resonance imaging predicts sustained clinical remission and decreased risk of surgery in Crohn’s disease.

Related Articles Bowel wall healing assessed using magnetic resonance imaging predicts sustained clinical remission and decreased risk of surgery in Crohn’s disease. J Gastroenterol. 2018 Aug 30;: Authors: Buisson A, Hordonneau C, Goutorbe F, Allimant C, Goutte M, Reymond M, Pereira B, Bommelaer G Abstract BACKGROUND: Endoscopic mucosal healing is considered as the best therapeutic target in Crohn’s disease (CD) as it is associated with better long-term outcomes. We investigated whether bowel wall healing (BWH) assessed using magnetic resonance imaging (MRI) could predict favorable outcomes and could be a potential…

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Editorial on “Inclusion of the mesentery in ileocolic resection for Crohn’s disease is associated with reduced surgical recurrence”.

Editorial on “Inclusion of the mesentery in ileocolic resection for Crohn’s disease is associated with reduced surgical recurrence”. J Crohns Colitis. 2018 Aug 20;: Authors: Buskens CJ, Bemelman WA PMID: 30137343 [PubMed – as supplied by publisher] PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/30137343?dopt=Abstract

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Male gender, active smoking and previous intestinal resection are risk factors of post-operative endoscopic recurrence in Crohn’s disease: results from a prospective cohort study.

Male gender, active smoking and previous intestinal resection are risk factors of post-operative endoscopic recurrence in Crohn’s disease: results from a prospective cohort study. Aliment Pharmacol Ther. 2018 Aug 20;: Authors: Auzolle C, Nancey S, Tran-Minh ML, Buisson A, Pariente B, Stefanescu C, Fumery M, Marteau P, Treton X, Hammoudi N, REMIND Study Group Investigators, Jouven X, Seksik P, Allez M Abstract BACKGROUND: After ileocaecal resection for Crohn’s disease (CD), inflammatory lesions frequently recur on the anastomosis and/or on the neo-terminal ileum. AIM: To identify predictors of early post-operative endoscopic…

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Editorial: post-operative complications in elderly onset inflammatory bowel disease-what is surgery, what is disease, and what is delay of surgery? Authors’ reply.

Related Articles Editorial: post-operative complications in elderly onset inflammatory bowel disease-what is surgery, what is disease, and what is delay of surgery? Authors’ reply. Aliment Pharmacol Ther. 2018 Aug;48(3):384-385 Authors: Savoye G, Fumery M, Gower-Rousseau C PMID: 29998504 [PubMed – in process] PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/29998504?dopt=Abstract

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Editorial: post-operative complications in elderly onset inflammatory bowel disease-what is surgery, what is disease, and what is delay of surgery?

Related Articles Editorial: post-operative complications in elderly onset inflammatory bowel disease-what is surgery, what is disease, and what is delay of surgery? Aliment Pharmacol Ther. 2018 Aug;48(3):383-384 Authors: Myrelid P PMID: 29998499 [PubMed – in process] PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/29998499?dopt=Abstract

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Accuracy of diffusion-weighted magnetic resonance imaging in detecting mucosal healing and treatment response, and in predicting surgery, in Crohn’s disease.

Accuracy of diffusion-weighted magnetic resonance imaging in detecting mucosal healing and treatment response, and in predicting surgery, in Crohn’s disease. J Crohns Colitis. 2018 Jul 09;: Authors: Thierry ML, Rousseau H, Pouillon L, Girard-Gavanier M, Baumann C, Lopez A, Danese S, Laurent V, Peyrin-Biroulet L Abstract Background and Aims: The Nancy score is a luminal Crohn’s disease (CD) activity index applied in diffusion-weighted magnetic resonance imaging (DW-MRI). We assessed the accuracy of the Nancy score in detecting mucosal healing and treatment response, and predicting surgery. Methods: Retrospective, single-centre study of…

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Predicting Risk of Postoperative Disease Recurrence in Crohn’s Disease: Patients With Indolent Crohn’s Disease Have Distinct Whole Transcriptome Profiles at the Time of First Surgery.

Related Articles Predicting Risk of Postoperative Disease Recurrence in Crohn’s Disease: Patients With Indolent Crohn’s Disease Have Distinct Whole Transcriptome Profiles at the Time of First Surgery. Inflamm Bowel Dis. 2018 Jul 05;: Authors: Cushing KC, Mclean R, McDonald KG, Gustafsson JK, Knoop KA, Kulkarni DH, Sartor RB, Newberry RD Abstract Background: Assessing risk of Crohn’s disease (CD) recurrence following ileocolic resection (ICR) is necessary to optimize medical management and prevent long-term complications. This study aimed to identify noninvasive markers that could predict postoperative disease activity. Methods: Inclusion criteria were…

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