Juvenile onset pernicious anemia, partial intestinal villous atrophy, ulcerative colitis, and squamous metaplasia of the stomach.

Related Articles Juvenile onset pernicious anemia, partial intestinal villous atrophy, ulcerative colitis, and squamous metaplasia of the stomach. Am J Gastroenterol. 1986 Sep;81(9):803-7 Authors: Tolia V, Chang CH, Emami A Abstract We report a case of a 13-yr-old white boy with juvenile onset pernicious anemia in association with IgG deficiency. He had marked gastric atrophy, intestinal metaplasia of the stomach, and an intractable antral ulcer that required surgery. In addition, his gastric mucosa showed evidence of a progressive squamous metaplasia. Diffuse squamous metaplasia of the stomach, a very rare gastric…

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A case presentation of hemolytic anemia in ulcerative colitis and review of the literature.

Related Articles A case presentation of hemolytic anemia in ulcerative colitis and review of the literature. Am J Gastroenterol. 1986 Oct;81(10):990-2 Authors: Basista MH, Roe DC Abstract Autoimmune hemolytic anemia associated with ulcerative colitis is a rare occurrence, and its management poses a therapeutic dilemma. Herein we present a case of ulcerative colitis involving an autoimmune hemolytic anemia and discuss the proposed mechanisms for the anemia. A review of past reported cases and their outcomes is included. In the past, a patient with autoimmune anemia unresponsive to corticosteroids was subjected…

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Coombs-positive autoimmune hemolytic anemia in ulcerative colitis.

Related Articles Coombs-positive autoimmune hemolytic anemia in ulcerative colitis. Dig Dis Sci. 1989 Sep;34(9):1457-61 Authors: Gumaste V, Greenstein AJ, Meyers R, Sachar DB Abstract Coombs-positive autoimmune hemolytic anemia is a rare complication of ulcerative colitis, occurring in fewer than 1% of cases. We have found eight patients with autoimmune hemolytic anemia in a series of 1150 hospitalized patients with ulcerative colitis (0.7%). There was a marked preponderance of female patients F:M = 7:1, in accord with previous reports. The hemolytic anemia appeared at a mean of 10 years after the…

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Autoimmune hemolytic anemia in ulcerative colitis. A case report with review of the literature.

Related Articles Autoimmune hemolytic anemia in ulcerative colitis. A case report with review of the literature. J Clin Gastroenterol. 1991 Aug;13(4):445-7 Authors: Veloso FT, Fraga J, Carvalho J, Dias LM, Salgado MC Abstract Autoimmune hemolytic anemia is a rare complication of ulcerative colitis. This report chronicles a patient successfully treated with steroids, and reviews treatment in previously reported cases. The fact that 21% of patients recovered with steroid therapy encourages a conservative approach before surgery is considered. PMID: 1918851 [PubMed – indexed for MEDLINE] PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/1918851?dopt=Abstract

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Treatment of anemia in inflammatory bowel disease with recombinant human erythropoietin: results in three patients.

Related Articles Treatment of anemia in inflammatory bowel disease with recombinant human erythropoietin: results in three patients. Gastroenterology. 1993 Jun;104(6):1828-31 Authors: Horina JH, Petritsch W, Schmid CR, Reicht G, Wenzl H, Silly H, Krejs GJ Abstract Inflammatory bowel disease (IBD) is often associated with anemia. Of 85 patients with IBD, 28 were anemic and had an inadequately low plasma erythropoietin (EPO) concentration. Three patients with a long-standing history of IBD and refractory chronic anemia (hemoglobin values < 10 g/dL, plasma EPO concentrations below 100 mU/mL) were treated with recombinant human…

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Atypical presentation of Crohn’s disease: severe, recurrent iron deficiency anemia dependent on blood transfusions.

Related Articles Atypical presentation of Crohn’s disease: severe, recurrent iron deficiency anemia dependent on blood transfusions. Am J Gastroenterol. 1994 Jan;89(1):113-5 Authors: Raju GS, Bardhan KD, Taylor PC, Harvey L, Rigby CC, Manasewitz S Abstract We report an unusual case of Crohn’s disease. Our subject, a 43-yr-old lady, presented with severe iron deficiency anemia, hypoproteinemia and lymphocytopenia, but without any clinical manifestations of Crohn’s disease either at presentation or during follow-up. She had recurrent episodes of severe iron deficiency anemia, repeatedly requiring blood transfusions (28 units in 20 months). She…

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Enterolithiasis, refractory anemia, and strictures of Crohn’s disease.

Related Articles Enterolithiasis, refractory anemia, and strictures of Crohn’s disease. J Clin Gastroenterol. 1994 Mar;18(2):105-8 Authors: Yuan JG, Sachar DB, Koganei K, Greenstein AJ Abstract In Crohn’s disease, multiple areas of small bowel stenosis are relatively common, but there are only 11 reported cases with stenosis complicated by enterolithiasis. We describe three patients with multiple strictures, enterolithiasis, and refractory iron deficiency anemia. The chronic anemia was severe, requiring multiple transfusions in two patients. One patient developed a perforation, and a second had cancer within one of the saccular dilatations between…

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Anemia in Crohn’s disease. Importance of inadequate erythropoietin production and iron deficiency.

Related Articles Anemia in Crohn’s disease. Importance of inadequate erythropoietin production and iron deficiency. Dig Dis Sci. 1994 Sep;39(9):1930-4 Authors: Gasché C, Reinisch W, Lochs H, Parsaei B, Bakos S, Wyatt J, Fueger GF, Gangl A Abstract Intestinal blood loss as well as chronic inflammation are regarded as the most important mechanisms in the pathogenesis of anemia in Crohn’s disease. In addition, cytokines such as interleukin-6 can suppress erythropoietin production. This study was performed to investigate the importance of iron status, inflammatory activity, and endogenous erythropoietin concentrations for the development…

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