Creeping Fat Assessed by Small Bowel MRI Is Linked to Bowel Damage and Abdominal Surgery in Crohn’s Disease.

Related Articles Creeping Fat Assessed by Small Bowel MRI Is Linked to Bowel Damage and Abdominal Surgery in Crohn’s Disease. Dig Dis Sci. 2018 Oct 01;: Authors: Althoff P, Schmiegel W, Lang G, Nicolas V, Brechmann T Abstract BACKGROUND: Crohn’s disease (CD) leads to bowel damage and surgery in a significant proportion of patients. AIMS: The aim of the study was to evaluate the predictive value of creeping fat assessed by small bowel MRI in CD patients. METHODS: CD patients undergoing small bowel MRI were included in a retrospective observational…

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Frequency, types, and treatment of anemia in Turkish patients with inflammatory bowel disease.

Frequency, types, and treatment of anemia in Turkish patients with inflammatory bowel disease. World J Gastroenterol. 2018 Sep 28;24(36):4186-4196 Authors: Bengi G, Keyvan H, Durmaz SB, Akpınar H Abstract AIM: To specify the type and prevalence of anemia along with a treatment approach for inflammatory bowel disease (IBD). METHODS: We conducted a retrospective study on 465 patients who were diagnosed with IBD and followed up at our hospital from June 2015 to June 2016 [male: 254, female: 211; average age: 47 ± 14.4; Crohn’s disease (CD): 257, Ulcerative Colitis (UC):…

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Family History is Associated With Increased Risk of Colorectal Cancer in Patients With Inflammatory Bowel Diseases.

Family History is Associated With Increased Risk of Colorectal Cancer in Patients With Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2018 Sep 26;: Authors: Samadder NJ, Valentine JF, Guthery S, Singh H, Bernstein CN, Leighton JA, Wan Y, Wong J, Boucher K, Pappas L, Rowe K, Burt RW, Curtin K, Smith KR Abstract BACKGROUND & OBJECTIVES: Individuals with inflammatory bowel diseases (IBD) carry an increased risk of developing colorectal cancer (CRC). Though family history of CRC is a well-established risk factor in healthy individuals, its role in IBD patients is less…

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Colon Surgery Risk With Corticosteroids Versus Immunomodulators or Biologics in Inflammatory Bowel Disease Patients With Clostridium difficile Infection.

Colon Surgery Risk With Corticosteroids Versus Immunomodulators or Biologics in Inflammatory Bowel Disease Patients With Clostridium difficile Infection. Inflamm Bowel Dis. 2018 Sep 26;: Authors: Solanky D, Pardi DS, Loftus EV, Khanna S Abstract Background: Inflammatory bowel disease (IBD) is an independent risk factor for Clostridium difficile infection (CDI), and CDI often precipitates IBD exacerbation. Because CDI cannot be distinguished clinically from an IBD exacerbation, management is difficult. We aimed to assess factors associated with adverse outcomes in IBD with CDI, including the role of escalating or de-escalating IBD therapy…

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Anti-tumor necrosis factor therapy decreases the risk of initial intestinal surgery after diagnosis of Crohn’s disease of inflammatory type.

Anti-tumor necrosis factor therapy decreases the risk of initial intestinal surgery after diagnosis of Crohn’s disease of inflammatory type. J Gastroenterol. 2018 Sep 22;: Authors: Nagata Y, Esaki M, Moriyama T, Hirano A, Umeno J, Maehata Y, Torisu T, Matsumoto T, Kitazono T Abstract BACKGROUND: Anti-tumor necrosis factor (TNF) therapy induces and maintains clinical remission in patients with Crohn’s disease (CD). However, the effect of anti-TNF therapy on the natural course of CD remains controversial. We aimed to investigate the effect of anti-TNF therapy on the initial intestinal surgery for…

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Outcomes of Endoscopic Balloon Dilation vs Surgical Resection for Primary Ileocolic Strictures in Patients With Crohn’s Disease.

Outcomes of Endoscopic Balloon Dilation vs Surgical Resection for Primary Ileocolic Strictures in Patients With Crohn’s Disease. Clin Gastroenterol Hepatol. 2018 Oct;16(10):1682-1683 Authors: Li JD, Xu XF, Xing H PMID: 30243356 [PubMed – in process] PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/30243356?dopt=Abstract

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Association Between Plasma Level of Collagen Type III alpha 1 Chain and Development of Strictures in Pediatric Patients With Crohn’s Disease.

Related Articles Association Between Plasma Level of Collagen Type III alpha 1 Chain and Development of Strictures in Pediatric Patients With Crohn’s Disease. Clin Gastroenterol Hepatol. 2018 Sep 10;: Authors: Ballengee CR, Stidham RW, Liu C, Kim MO, Prince J, Mondal K, Baldassano R, Dubinsky M, Markowitz J, Leleiko N, Hyams J, Denson L, Kugathasan S Abstract BACKGROUND & AIMS: There are few serum biomarkers to identify patients with Crohn’s disease (CD) who are at risk for stricture development. The extracellular matrix components, collagen type III alpha 1 chain (COL3A1)…

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Review article: the relationship between obesity, bariatric surgery, and inflammatory bowel disease.

Review article: the relationship between obesity, bariatric surgery, and inflammatory bowel disease. Aliment Pharmacol Ther. 2018 Sep 04;: Authors: Cañete F, Mañosa M, Clos A, Cabré E, Domènech E Abstract BACKGROUND: The convoluted relationship between obesity, bariatric surgery and inflammatory bowel disease (IBD) is of increasing interest. AIM: To analyse evidence regarding the role of bariatric surgery in the development of de novo IBD and its impact on clinical outcomes and safety in patients with established IBD. METHODS: A PubMed/Medline search was performed to identify studies reporting the development of…

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Bowel wall healing assessed using magnetic resonance imaging predicts sustained clinical remission and decreased risk of surgery in Crohn’s disease.

Related Articles Bowel wall healing assessed using magnetic resonance imaging predicts sustained clinical remission and decreased risk of surgery in Crohn’s disease. J Gastroenterol. 2018 Aug 30;: Authors: Buisson A, Hordonneau C, Goutorbe F, Allimant C, Goutte M, Reymond M, Pereira B, Bommelaer G Abstract BACKGROUND: Endoscopic mucosal healing is considered as the best therapeutic target in Crohn’s disease (CD) as it is associated with better long-term outcomes. We investigated whether bowel wall healing (BWH) assessed using magnetic resonance imaging (MRI) could predict favorable outcomes and could be a potential…

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Editorial on “Inclusion of the mesentery in ileocolic resection for Crohn’s disease is associated with reduced surgical recurrence”.

Editorial on “Inclusion of the mesentery in ileocolic resection for Crohn’s disease is associated with reduced surgical recurrence”. J Crohns Colitis. 2018 Aug 20;: Authors: Buskens CJ, Bemelman WA PMID: 30137343 [PubMed – as supplied by publisher] PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/30137343?dopt=Abstract

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