The influence of microscopic inflammation at resection margins on early postoperative endoscopic recurrence after ileocaecal resection for Crohn’s disease.

Related Articles The influence of microscopic inflammation at resection margins on early postoperative endoscopic recurrence after ileocaecal resection for Crohn’s disease. J Crohns Colitis. 2019 Sep 10;: Authors: Poredska K, Kunovsky L, Marek F, Kala Z, Prochazka V, Dolina J, Zboril V, Kovalcikova P, Pavlik T, Jabandziev P, Pavlovsky Z, Vlazny J, Mitas L Abstract BACKGROUND AND AIMS: The pathogenesis and risk factors for early postoperative endoscopic recurrence of Crohn’s disease (CD) remain unclear. Thus, this study aimed to identify whether histological inflammation at the resection margins after an ileocaecal…

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Cancer Risk in Inflammatory Bowel Disease: A 6-Year Prospective Multicenter Nested Case-Control IG-IBD Study.

Cancer Risk in Inflammatory Bowel Disease: A 6-Year Prospective Multicenter Nested Case-Control IG-IBD Study. Inflamm Bowel Dis. 2019 Jul 19;: Authors: Biancone L, Armuzzi A, Scribano ML, Castiglione F, D’incà R, Orlando A, Papi C, Daperno M, Vecchi M, Riegler G, Fries W, Alvisi P, Meucci G, Mocciaro F, Rogai F, Festa S, Guidi L, Testa A, Spina L, Renna S, Viola A, Patturelli M, Di Mitri R, Frankovic I, Calabrese E, Petruzziello C, De Cristofaro E, Sena G, Ruffa A, Neri B, Rossi A, Italian Group for the Study…

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Oral Curcumin No More Effective Than Placebo in Preventing Recurrence of Crohn’s Disease After Surgery in a Randomized Controlled Trial.

Oral Curcumin No More Effective Than Placebo in Preventing Recurrence of Crohn’s Disease After Surgery in a Randomized Controlled Trial. Clin Gastroenterol Hepatol. 2019 Aug 27;: Authors: Bommelaer G, Laharie D, Nancey S, Hebuterne X, Roblin X, Nachury M, Peyrin-Biroulet L, Fumery M, Richard D, Pereira B, Goutte M, Buisson A, POPCUR study group Abstract BACKGROUND AND AIMS: Recurrence of Crohn’s disease (CD) after surgery is a major concern. Curcumin has anti-inflammatory properties and induces endoscopic remission in patients with ulcerative colitis. We investigated the efficacy of curcumin vs placebo…

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Colorectal cancer surveillance in inflammatory bowel disease: Practice guidelines and recent developments.

Related Articles Colorectal cancer surveillance in inflammatory bowel disease: Practice guidelines and recent developments. World J Gastroenterol. 2019 Aug 14;25(30):4148-4157 Authors: Clarke WT, Feuerstein JD Abstract Patients with long-standing inflammatory bowel disease (IBD) involving at least 1/3 of the colon are at increased risk for colorectal cancer (CRC). Advancements in CRC screening and surveillance and improved treatment of IBD has reduced CRC incidence in patients with ulcerative colitis and Crohn’s colitis. Most cases of CRC are thought to arise from dysplasia, and recent evidence suggests that the majority of dysplastic…

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Intestinal resection rates in Crohn’s disease decline across two different epidemiological areas: a consistent observation not merely due to introduction of anti-TNFα.

Related Articles Intestinal resection rates in Crohn’s disease decline across two different epidemiological areas: a consistent observation not merely due to introduction of anti-TNFα. Gut. 2019 Aug 14;: Authors: Beelen EMJ, van der Woude CJ, de Vries AC PMID: 31413165 [PubMed – as supplied by publisher] PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/31413165?dopt=Abstract

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Rates of Adverse IBD-Related Outcomes for Patients With IBD and Concomitant Prostate Cancer Treated With Radiation Therapy.

Rates of Adverse IBD-Related Outcomes for Patients With IBD and Concomitant Prostate Cancer Treated With Radiation Therapy. Inflamm Bowel Dis. 2019 Aug 14;: Authors: Feagins LA, Kim J, Chandrakumaran A, Gandle C, Naik KH, Cipher DJ, Hou JK, Yao MD, Gaidos JKJ Abstract BACKGROUND: Patients with inflammatory bowel disease (IBD) may be at higher risk for complications from radiation treatment for prostate cancer. However, available data are limited, and controversy remains regarding the best treatment approach for IBD patients who develop prostate cancer. METHODS: A retrospective cohort study across 4…

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Complications while waiting for IBD surgery- short report.

Related Articles Complications while waiting for IBD surgery- short report. J Crohns Colitis. 2019 Aug 12;: Authors: Wasmann KA, IBD study group Amsterdam UMC, location AMC Abstract BACKGROUND AND AIMS: While striving to meet the quality standards for oncological care, hospitals prioritize oncological procedures more frequently, resulting in longer waiting times to surgery for benign diseases like inflammatory bowel disease (IBD). The aim of this short-report is to highlight the potential consequences of a longer interval to surgery for IBD patients. METHODS: The mean waiting time to elective surgery for…

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Portomesenteric Venous Thrombosis in Patients Undergoing Surgery for Medically Refractory Ulcerative Colitis.

Related Articles Portomesenteric Venous Thrombosis in Patients Undergoing Surgery for Medically Refractory Ulcerative Colitis. Inflamm Bowel Dis. 2019 Aug 02;: Authors: Kayal M, Radcliffe M, Plietz M, Rosman A, Greenstein A, Khaitov S, Sylla P, Dubinsky MC Abstract BACKGROUND: Portomesenteric venous thrombosis (PMVT) is an under-recognized complication of colorectal surgery. The aim of this study was to describe the rate and risk factors for PMVT in patients undergoing surgery for medically refractory ulcerative colitis (UC). METHODS: A retrospective review of medically refractory UC patients who underwent surgery between January 2010…

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Interval Colorectal Cancer in Inflammatory Bowel Disease: The Role of Guideline Adherence.

Related Articles Interval Colorectal Cancer in Inflammatory Bowel Disease: The Role of Guideline Adherence. Dig Dis Sci. 2019 Aug 01;: Authors: Burke KE, Nayor J, Campbell EJ, Ananthakrishnan AN, Khalili H, Richter JM Abstract BACKGROUND: Factors associated with interval colorectal cancer (CRC) development in the inflammatory bowel disease (IBD) population remain unclear. AIMS: Among a cohort of patients with interval CRC, we aimed to evaluate IBD characteristics, colonoscopy quality indicators, and surveillance guideline adherence. METHODS: We performed a retrospective review of IBD- and non-IBD-associated interval CRCs diagnosed between January 2007…

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Letter: pre-operative anti-TNF therapy in Crohn’s disease is not associated with increased complications following elective surgery.

Related Articles Letter: pre-operative anti-TNF therapy in Crohn’s disease is not associated with increased complications following elective surgery. Aliment Pharmacol Ther. 2019 Aug;50(4):467-468 Authors: Istl A, Yang ML, Fleshner KA, Parker CE, Guizzetti L, Singh S, Jairath V PMID: 31359469 [PubMed – in process] PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/31359469?dopt=Abstract

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