Maintenance Adalimumab Concentrations Are Associated with Biochemical, Endoscopic, and Histologic Remission in Inflammatory Bowel Disease.

Related Articles Maintenance Adalimumab Concentrations Are Associated with Biochemical, Endoscopic, and Histologic Remission in Inflammatory Bowel Disease. Dig Dis Sci. 2018 Jul 13;: Authors: Juncadella A, Papamichael K, Vaughn BP, Cheifetz AS Abstract BACKGROUND: A treat-to-target therapeutic approach is emerging as the new standard of care for treating inflammatory bowel disease (IBD), Crohn’s disease (CD), and ulcerative colitis (UC). AIMS: We aimed to investigate the association of serum adalimumab concentrations during maintenance therapy with biochemical, endoscopic, and histologic remission in IBD. METHODS: This retrospective multicenter study included consecutive IBD patients…

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Pulmonary Arterial Hypertension Associated With the Chinese Herb Indigo Naturalis for Ulcerative Colitis: It May Be Reversible.

Related Articles Pulmonary Arterial Hypertension Associated With the Chinese Herb Indigo Naturalis for Ulcerative Colitis: It May Be Reversible. Gastroenterology. 2018 Jul 09;: Authors: Nishio M, Hirooka K, Doi Y PMID: 30001991 [PubMed – as supplied by publisher] PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/30001991?dopt=Abstract

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Editorial: post-operative complications in elderly onset inflammatory bowel disease-what is surgery, what is disease, and what is delay of surgery? Authors’ reply.

Related Articles Editorial: post-operative complications in elderly onset inflammatory bowel disease-what is surgery, what is disease, and what is delay of surgery? Authors’ reply. Aliment Pharmacol Ther. 2018 Aug;48(3):384-385 Authors: Savoye G, Fumery M, Gower-Rousseau C PMID: 29998504 [PubMed – in process] PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/29998504?dopt=Abstract

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Letter: vedolizumab drug levels in cord and maternal blood in women with inflammatory bowel disease-authors’ reply.

Related Articles Letter: vedolizumab drug levels in cord and maternal blood in women with inflammatory bowel disease-authors’ reply. Aliment Pharmacol Ther. 2018 Aug;48(3):388-389 Authors: Mahadevan U, Vermeire S, Lasch K, Abhyankar B, Bhayat F, Blake A, Dubinsky M PMID: 29998501 [PubMed – in process] PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/29998501?dopt=Abstract

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Editorial: post-operative complications in elderly onset inflammatory bowel disease-what is surgery, what is disease, and what is delay of surgery?

Related Articles Editorial: post-operative complications in elderly onset inflammatory bowel disease-what is surgery, what is disease, and what is delay of surgery? Aliment Pharmacol Ther. 2018 Aug;48(3):383-384 Authors: Myrelid P PMID: 29998499 [PubMed – in process] PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/29998499?dopt=Abstract

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Gastrointestinal disease burden and mortality: A public hospital based study from 2005 to 2014.

Gastrointestinal disease burden and mortality: A public hospital based study from 2005 to 2014. J Gastroenterol Hepatol. 2018 Jul 11;: Authors: Chan JSH, Chao ACW, Cheung VCH, Wong SSK, Tang W, Wu JCY, Chan HLY, Chan FKL, Sung JJY, Ng SC Abstract BACKGROUND AND AIM: Gastrointestinal (GI) diseases account for substantial morbidity, mortality and health care utilization. This public hospital based study assessed the incidence and time trend of hospitalization and mortality of major GI diseases over one decade. METHODS: We conducted an observational study using population-wide database managed by…

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Limited Health Literacy Is Associated With Worse Patient-Reported Outcomes in Inflammatory Bowel Disease.

Related Articles Limited Health Literacy Is Associated With Worse Patient-Reported Outcomes in Inflammatory Bowel Disease. Inflamm Bowel Dis. 2018 Jul 10;: Authors: Tormey LK, Reich J, Chen YS, Singh A, Lipkin-Moore Z, Yu A, Weinberg J, Farraye FA, Paasche-Orlow MK Abstract Background: Patients with inflammatory bowel disease (IBD) face complex health tasks and decisions. Limited health literacy is a risk factor for poor health outcomes, but this has not been examined in IBD. This study aims to assess the role of health literacy for patients with IBD. Methods: We prospectively…

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Placebo Rates in Randomized Controlled Trials of Pouchitis Therapy.

Placebo Rates in Randomized Controlled Trials of Pouchitis Therapy. Dig Dis Sci. 2018 Jul 11;: Authors: Athayde J, Davies SC, Parker CE, Guizzetti L, Ma C, Khanna R, Feagan BG, Jairath V Abstract BACKGROUND: Approximately half of the patients with ulcerative colitis (UC) who undergo restorative proctocolectomy develop pouchitis within 10 years of surgery. Currently, there are no approved pouchitis treatments. It is important to quantify, and ultimately minimize, placebo rates to design and conduct efficient pouchitis trials. AIMS: To quantify the placebo rate observed in pouchitis randomized controlled trials (RCTs)…

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