Differential diagnosis of inflammatory bowel disease: imitations and complications.

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Differential diagnosis of inflammatory bowel disease: imitations and complications. Lancet Gastroenterol Hepatol. 2018 Sep;3(9):644-653 Authors: Gecse KB, Vermeire S Abstract Inflammatory bowel disease (IBD) is characterised by episodes of relapse and periods of remission. However, the clinical features, such as abdominal pain, diarrhoea, and rectal bleeding, are not specific. Therefore, the differential diagnosis can include a broad spectrum of inflammatory or infectious diseases that mimic IBD, as well as others that might complicate existing IBD. In this Review, we provide an overview of ileocolitis of diverse causes that are relevant…

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New Methylation Biomarker Panel for Early Diagnosis of Dysplasia or Cancer in High-Risk Inflammatory Bowel Disease Patients.

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Related Articles New Methylation Biomarker Panel for Early Diagnosis of Dysplasia or Cancer in High-Risk Inflammatory Bowel Disease Patients. Inflamm Bowel Dis. 2018 Aug 07;: Authors: Azuara D, Aussó S, Rodriguez-Moranta F, Guardiola J, Sanjuan X, Lobaton T, Boadas J, Piqueras M, Monfort D, Guinó E, Moreno V, Capellá G, de Oca J Abstract Background: The risk of developing colorectal cancer (CRC) is increased in patients with inflammatory bowel disease (IBD) of the colon. The aim of the study was to evaluate the effectiveness of selected methylation gene panel for…

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Clinical Practice Guideline for the Medical Management of Perianal Fistulizing Crohn’s Disease: The Toronto Consensus.

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Related Articles Clinical Practice Guideline for the Medical Management of Perianal Fistulizing Crohn’s Disease: The Toronto Consensus. Inflamm Bowel Dis. 2018 Aug 06;: Authors: Steinhart AH, Panaccione R, Targownik L, Bressler B, Khanna R, Marshall JK, Afif W, Bernstein CN, Bitton A, Borgaonkar M, Chauhan U, Halloran B, Jones J, Kennedy E, Leontiadis GI, Loftus EV, Meddings J, Moayyedi P, Murthy S, Plamondon S, Rosenfeld G, Schwartz D, Seow CH, Williams C Abstract Background: Fistulas occur in about 25% of patients with Crohn’s disease (CD) and can be difficult to…

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Functional gastrointestinal symptoms in patients with inflammatory bowel disease: A clinical challenge.

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Related Articles Functional gastrointestinal symptoms in patients with inflammatory bowel disease: A clinical challenge. Clin Gastroenterol Hepatol. 2018 Aug 09;: Authors: Colombel JF, Shin A, Gibson PR Abstract DESCRIPTION: The purpose of this clinical practice update review is to describe key principles in the diagnosis and management of functional gastrointestinal (GI) symptoms in patients with inflammatory bowel disease (IBD). METHODS: The evidence and best practices summarized in this manuscript are based on relevant scientific publications, systematic reviews, and expert opinion where applicable. BEST PRACTICE ADVICE 1: A stepwise approach to…

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Enteral nutrition for maintenance of remission in Crohn’s disease.

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Related Articles Enteral nutrition for maintenance of remission in Crohn’s disease. Cochrane Database Syst Rev. 2018 Aug 11;8:CD005984 Authors: Akobeng AK, Zhang D, Gordon M, MacDonald JK Abstract BACKGROUND: Prevention of relapse is a major issue in the management of quiescent Crohn’s disease (CD). Current therapies (e.g. methotrexate, biologics, 6-mercaptopurine and azathioprine) may be effective for maintaining remission in CD, but these drugs may cause significant adverse events. Interventions that are effective and safe for maintenance of remission in CD are desirable. OBJECTIVES: The primary objectives were to evaluate the…

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