Thiopurines prevented surgical recurrence in patients with Crohn’s disease after intestinal resection: strategy based on risk stratification.

Related Articles Thiopurines prevented surgical recurrence in patients with Crohn’s disease after intestinal resection: strategy based on risk stratification. J Gastroenterol Hepatol. 2017 Aug 14;: Authors: Guo J, Chen BL, Chen ZH, Luo XP, Qiu Y, Zhang SH, Feng R, He Y, Zeng ZR, Song XM, Ben-Horin S, Mao R, Chen MH Abstract BACKGROUND: Thiopurines (TPs) are effective in reducing risk of clinical and endoscopic recurrence in postoperative patients with Crohn’s disease (CD). However, whether TPs could prevent surgical recurrence (SR) remains unknown. AIM: To explore whether TPs could prevent…

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Safety of herpes zoster vaccination among inflammatory bowel disease patients being treated with anti-TNF medications.

Safety of herpes zoster vaccination among inflammatory bowel disease patients being treated with anti-TNF medications. Aliment Pharmacol Ther. 2017 Aug 14;: Authors: Khan N, Shah Y, Trivedi C, Lewis JD Abstract BACKGROUND: The risk of herpes zoster (HZ) is elevated in inflammatory bowel disease (IBD) patients treated with anti-TNF medications. While it is optimal to give herpes zoster vaccine prior to initiation of therapy clinical circumstances may not always allow this. AIM: To determine the safety of giving herpes zoster vaccine while patients are on anti-TNF therapy. METHODS: We conducted…

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Integrated Analysis of Biopsies from Inflammatory Bowel Disease Patients Identifies SAA1 as a Link Between Mucosal Microbes with TH17 and TH22 Cells.

Integrated Analysis of Biopsies from Inflammatory Bowel Disease Patients Identifies SAA1 as a Link Between Mucosal Microbes with TH17 and TH22 Cells. Inflamm Bowel Dis. 2017 Aug 09;: Authors: Tang MS, Bowcutt R, Leung JM, Wolff MJ, Gundra UM, Hudesman D, Malter LB, Poles MA, Chen LA, Pei Z, Neto AG, Abidi WM, Ullman T, Mayer L, Bonneau RA, Cho I, Loke P Abstract BACKGROUND: Inflammatory bowel diseases (IBD) are believed to be driven by dysregulated interactions between the host and the gut microbiota. Our goal is to characterize and…

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Limited uptake of ulcerative colitis ‘treat to target’ recommendations in real-world practice.

Limited uptake of ulcerative colitis ‘treat to target’ recommendations in real-world practice. J Gastroenterol Hepatol. 2017 Aug 14;: Authors: Bryant RV, Costello SP, Schoeman S, Sathananthan D, Knight E, Lau SY, Schoeman MN, Mountifield R, Tee D, Travis SPL, Andrews JM Abstract BACKGROUND & AIMS: A ‘Treat to Target’ (T2T) approach has been proposed for ulcerative colitis (UC), with a target of combined clinical and endoscopic remission. The aim of the study was evaluate the extent to which proposed targets are achieved in real-world care, along with clinician perceptions and…

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Predictors of long-term outcomes in patients with acute severe colitis: A Northern Indian cohort study.

Related Articles Predictors of long-term outcomes in patients with acute severe colitis: A Northern Indian cohort study. J Gastroenterol Hepatol. 2017 Aug 12;: Authors: Jain S, Kedia S, Sethi T, Bopanna S, Yadav DP, Goyal S, Padhan R, Venigalla PM, Sahni P, Dash NR, Pal S, Makharia G, Travis SPL, Ahuja V Abstract BACKGROUND AND AIM: Knowledge of long-term outcomes following an index episode of acute severe colitis (ASC) can help informed decision-making at a time of acute exacerbation especially when colectomy is an option. We aimed to identify long-term…

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